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Orthopedic Surgery Board Review MCQs: Arthroplasty, Trauma & Spine Part 255

OITE & ABOS Orthopedic Board Exam MCQs: Shoulder, Elbow, Trauma & Fractures - Part 2

27 Apr 2026 232 min read 63 Views
OITE & ABOS Orthopedic Board Prep: Practice Exam Part 2

Key Takeaway

This interactive quiz offers 100 verified, high-yield MCQs for orthopedic surgeons and residents preparing for OITE/AAOS/ABOS board certification. Mimicking exam format, it provides detailed explanations. Practice in Study or Exam Mode to master essential topics, ensuring comprehensive board exam preparation.

About This Board Review Set

This is Part 2 of the comprehensive OITE and AAOS Orthopedic Surgery Board Review series authored by Dr. Mohammed Hutaif, Consultant Orthopedic & Spine Surgeon.

This set has been strictly audited and contains 100 100% verified, high-yield multiple-choice questions (MCQs) modelled on the exact format of the Orthopaedic In-Training Examination (OITE) and the American Academy of Orthopaedic Surgeons (AAOS) board examinations.

How to Use the Interactive Quiz

Two distinct learning modes are available:

  • Study Mode — After selecting an answer, you immediately see whether you are correct or incorrect, together with a full clinical explanation and literature references.
  • Exam Mode — All feedback is hidden until you click Submit & See Results. A live timer tracks elapsed time. A percentage score and detailed breakdown are displayed upon submission.

Pro Tip: Use keyboard shortcuts A–E to select options, F to flag a question for review, and Enter to jump to the next unanswered question.

Topics Covered in Part 2

This module focuses heavily on: Elbow, Fracture, Shoulder, Trauma.

Sample Questions from This Set

Sample Question 1: Figure 51 shows the radiograph of a 42-year-old construction worker who has pain and limited motion in his dominant elbow. Management consisting of nonsteroidal anti-inflammatory drugs and cortisone has failed to provide relief. What is the...

Sample Question 2: A 26-year-old man sustains a displaced bimalleolar fracture by sliding into second base while playing baseball. Following initial closed reduction and splinting of the fracture, moderate swelling is noted. What is the safest time to perform...

Sample Question 3: A 61-year-old man has a symptomatic bunionette that is refractory to nonsurgical management. A radiograph is shown in Figure 6. What is the optimal surgical correction?...

Sample Question 4: Figure 23 is the radiograph of a 22-year-old woman who was involved in a motor vehicle collision. She reports isolated pain in her left shoulder. She is hemodynamically stable, respiring comfortably, and neurovascularly intact. Based on the...

Sample Question 5: A 36-year-old woman was injured in a train derailment. She has a significant open depressed skull fracture with active bleeding, a hemopneumothorax, and blood in the left upper quadrant and colic gutter by Focused Assessment with Sonography...

Why Active MCQ Practice Works

Evidence consistently demonstrates that active recall through spaced MCQ practice yields substantially greater long-term retention than passive reading alone (Roediger & Karpicke, 2006). All questions in this specific module have been algorithmically verified for clinical integrity and complete explanations.

Comprehensive 100-Question Exam


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Question 1

Figure 51 shows the radiograph of a 42-year-old construction worker who has pain and limited motion in his dominant elbow. Management consisting of nonsteroidal anti-inflammatory drugs and cortisone has failed to provide relief. What is the next most appropriate step in treatment?





Explanation

DISCUSSION: The patient has symptomatic primary osteoarthritis of the elbow with multiple loose bodies.  Given his age and occupation, an elbow arthroplasty is not an option.  Arthroscopic debridement and removal of loose bodies has been shown to be effective for osteoarthritis of the elbow.
REFERENCES: Gramstad GD, Galatz LM: Management of elbow osteoarthritis.  J Bone Joint Surg Am 2006;88:421-430.
Steinmann SP, King GJ, Savoie FH III, et al: Arthroscopic treatment of the arthritic elbow. 

J Bone Joint Surg Am 2005;87:2114-2121.

Question 2

A 26-year-old man sustains a displaced bimalleolar fracture by sliding into second base while playing baseball. Following initial closed reduction and splinting of the fracture, moderate swelling is noted. What is the safest time to perform surgery?





Explanation

DISCUSSION: Following any closed fracture, the most important determinant for the timing of surgery is the condition of the soft tissues and especially the skin.  The best determinant of appropriate soft-tissue condition is the presence of wrinkling of the skin (wrinkle sign) at the site of the incision.  A wrinkle sign is present when all the interstitial edema has left the skin; this may take up to 14 to 21 days of elevation.  Any abrasion must be epithelialized so that there are no bacteria left at the site.  To date, no other method of soft-tissue viability measurement has been shown to be of any clinical benefit.
REFERENCES: Stover MD, Kellam JF: Articular fractures: Principles, in Ruedi TP, Murphy WM (eds): AO Principles of Fracture Management.  Stuttgart, Thieme, 2000, pp 105-119.
Hahn DM, Colton CL, Malleolar fractures, in Ruedi TP, Murphy WM (eds): AO Principles of Fracture Management.  Stuttgart, Thieme, 2000, pp 559-581.
Tile M: Fractures of the ankle, in Schatzker J, Tile M (eds): Rationale of Operative Fracture Care, ed 2.  Berlin, Springer-Verlag, 1998, pp 523-561.

Question 3

A 61-year-old man has a symptomatic bunionette that is refractory to nonsurgical management. A radiograph is shown in Figure 6. What is the optimal surgical correction?





Explanation

DISCUSSION: The patient has a bunionette with a large 4-5 intermetatarsal angle.  This requires not only ostectomy of the lateral prominence but metatarsal osteotomy to decrease the intermetatarsal angle.  Excising the head results in a flail joint and creates the possibility of a transfer lesion.  Condylectomy can reduce plantar pressures but does not address the bunionette.  The joint surface is well maintained, thus there are no indications for resection. 
REFERENCES: Coughlin MJ: Treatment of bunionette deformity with longitudinal diaphyseal osteotomy with distal soft tissue repair.  Foot Ankle 1991;11:195-203.
Koti M, Maffulli N: Bunionette.  J Bone Joint Surg Am 2001;83:1076-1082.

Question 4

Figure 23 is the radiograph of a 22-year-old woman who was involved in a motor vehicle collision. She reports isolated pain in her left shoulder. She is hemodynamically stable, respiring comfortably, and neurovascularly intact. Based on these findings, which of the following statements regarding treatment is most appropriate?





Explanation

The patient has sustained an isolated, closed, transverse fracture of the middle third of the clavicle with greater than 100% displacement and greater than 2 cm of shortening. Whereas the traditional treatment of clavicle fractures has been overwhelmingly conservative, recent reports suggest that surgical fixation should be considered for certain injury patterns. The union rates of displaced clavicle fractures are more recently noted to be approximately 85%, which is lower than the traditional literature. In a prospective randomized trial of clavicle fractures with greater than 100% displacement, union rates were higher and functional outcomes were better at all time points up to 1 year after injury in the surgical group when compared with nonsurgical management.

Question 5

A 36-year-old woman was injured in a train derailment. She has a significant open depressed skull fracture with active bleeding, a hemopneumothorax, and blood in the left upper quadrant and colic gutter by Focused Assessment with Sonography for Trauma (FAST) examination. Additionally, she has the pelvic injury seen on the CT scans in Figures 18a and 18b. The mortality rate for this patient approaches





Explanation

DISCUSSION: Mortality following trauma that requires surgical intervention for head, chest, and abdominal injury exceeds 90%.  The type of pelvic fracture is a predictor of associated injury, blood requirements, and overall mortality.  AP III pelvic fractures require the most blood, and are associated with significant abdominal trauma and shock.  Lateral compression pelvic fractures are more associated with head, chest, and occasionally abdominal trauma, and mortality often occurs from associated injuries.
REFERENCES: Dalal SA, Burgess AR, Siegel JH, et al: Pelvic fracture in multiple trauma: Classification by mechanism is key to pattern of organ injury, resuscitative requirements and outcome.  J Trauma 1989;29:981-1000.
Eastridge BJ, Burgess AR: Pedestrian pelvic fractures: 5-year experience of a major urban trauma center.  J Trauma 1997;42:695-700.
Gilliland MD, Ward RE, Barton RM, et al: Factors affecting mortality in pelvic fractures. 

J Trauma 1982;22:691-693.

Question 6

What vessel is marked with an asterisk in Figure 44?





Explanation

DISCUSSION: The superior gluteal artery is a branch of the posterior division of the internal iliac artery and exits the pelvis through the greater sciatic notch.  It can be injured as a result of a pelvic ring fracture or acetabular fracture that has a fracture of the posterior column.
REFERENCES: Agur AM, Dalley AF (eds): Grant’s Atlas of Anatomy, ed 12.  Philadelphia, PA, Lippincott Williams and Wilkins, 2008.
Uflacker R: Atlas of Vascular Anatomy: An Angiographic Approach, ed 2.  Philadelphia, PA, Lippincott Williams and Wilkins, 2006.

Question 7

A 29-year-old male sustains the isolated lower extremity injury shown in Figure A. During open reduction, what structure must be kept intact in order to protect the remaining blood supply to the talar body?





Explanation

Figure A represents a type 3 Hawkins talar neck fracture. A type 3 injury is defined as a displaced fracture of the talar neck with dislocation of body of talus from both the subtalar joint and the tibiotalar joint. In these injuries, the talar body fragment typically rotates around intact deltoid ligament fibers to lie in soft tissues with the fracture surface pointing laterally and cephalad. Often, the deltoid branch of the posterior tibial artery, which lies between the leaves of the deltoid ligament and supplies up to 1/2 of the medial talar body, is the only remaining blood supply. Therefore, the deltoid ligament must be preserved to lower the risk of avascular necrosis. When performing a medial malleolar osteotomy, the deltoid ligament must remain in continuity with the malleolus to prevent disruption of the blood supply.
The review article by Fortin et al discusses talar blood supply, injury mechanisms and classifications, and treatment options. They state that the main artery to the body of the talus is the artery of the tarsal canal, which is a branch of the posterior tibial artery. The peroneal and anterior tibial artery also contribute branches to the talus.
Illustration A and B show the arterial network of the talus.

OrthoCash 2020

Question 8

Which treatment of the current fracture will provide the best long-term outcome?




Explanation

DISCUSSION
Many patients with mild dominant OI (the most common type) appear “normal,” and a diagnosis cannot be made without a careful personal history, family history, and observance of blue sclera. More than 3 fractures during childhood places someone outside of the mean and should merit further investigation. There is no sign of rickets on this radiograph (physeal widening/cupping). Similarly, the history and examination finding of blue sclera in the patient and his mother should raise concern for OI. Many parents of children with OI have inappropriately been accused of abuse despite obvious examination, radiograph, and family history findings that suggest OI. Low-energy mechanisms that create displaced fractures are a hallmark of OI and do not in isolation raise suspicion for nonaccidental trauma.
Based on the history and examination, mild-form OI caused by a defect in the type I collagen gene is most likely. Defects in type II collagen genes affect articular cartilage and cause epiphyseal dysplasia. Defects in the LEPRE cause severe-form OI involving clinically bowed limbs, marked short stature, and white sclera. There is no sign on radiographs of rickets, so severe vitamin D deficiency is not present. The history, examination, and radiographs all point toward OI/osteoporosis rather than nonaccidental trauma.
Peri-implant fractures occur because of a difference in elasticity between the bone with implants and the bone adjacent to it without implants. This is particularly important in the setting of osteoporotic bone in which the difference in elasticity and rigidity will be much more pronounced than in normal bone. Load-sharing implants are preferred when possible. The original fracture occurred proximal to the current fracture in the middle of the plated bone and looks healed with no sign of infection.
This fracture is in unacceptable alignment with subluxation of the radiocapitellar joint. The plates are bent, so closed reduction will not solve the alignment problem. In early childhood, load-sharing implants (flexible rods or wires) should be used to solve the elasticity mismatch that contributed to the current fracture.

CLINICAL SITUATION FOR QUESTIONS 51 THROUGH 54
Figures 51a through 51c are the radiographs of an 8-year-old boy with a shoulder deformity and limited cervical range of motion. He has no significant medical problems and plays baseball, pitching with his right arm. His active shoulder abduction is 180 degrees on the left and 150 degrees on the right.

Question 9

A patient has had a locked posterior dislocation of the shoulder for the past 6 months. After undergoing total shoulder arthroplasty that includes adequate anterior releases and posterior capsulorrhaphy, the patient still exhibits posterior instability intraoperatively. The postoperative rehabilitation regimen should include





Explanation

DISCUSSION: Achieving stability in chronic locked posterior dislocations of the shoulder remains a difficult challenge.  Intraoperative measures include decreased humeral retroversion, anterior releases, and posterior capsular tightening.  Postoperative rehabilitation is of equal importance.  Immobilization in an external rotation brace (10 degrees to 15 degrees) with the arm at the side for 4 to 6 weeks is recommended to decrease tension in the posterior capsule.  When passive range-of-motion exercises are instituted, they should be performed in the plane of the scapula to avoid stress posteriorly.  Internal rotation and supine elevation should be avoided for similar reasons.
REFERENCES: Hawkins RJ, Neer CS II, Pianta RM, Mendoza FX: Locked posterior dislocation of the shoulder.  J Bone Joint Surg Am 1987;69:9-18.
Loebenberg MI, Cuomo F: The treatment of chronic anterior and posterior dislocations of the glenohumeral joint and associated articular surface defects.  Orthop Clin North Am 2000;31:23-24.

Question 10

Which of the following growth factors binds and activates the lipoprotein receptor-related protein 5/6 (LRP5/6) during bone development? Review Topic





Explanation

Wnt and Hedgehog (Hh) signaling pathways are key regulators of bone formation. Mutations in the Wnt and Hh pathways result in skeletal malformations as well as osteoarthritis. Wnts are a large family of secreted proteins (19 different members in the human genome) that transduce their signal through several pathways. The most studied of these pathways is the Wnt/beta-catenin pathway, in which Wnt protein binds to the LRP5/6 receptor at the cell surface and activates an intracellular cascade. This cascade leads to translocation of beta-catenin into the nucleus to activate transcription of genes that control osteoblast differentiation. Agents that stimulate this pathway are under investigation for treatment of osteoporosis.

Question 11

A 10-year-old boy has a painful, swollen knee after falling off his bicycle. Examination reveals that the knee is held in 45 degrees of flexion, and any attempt to actively or passively extend the knee produces pain and muscle spasms. A lateral radiograph is shown in Figure 4. What is the most likely diagnosis?





Explanation

DISCUSSION: This is a typical patellar sleeve fracture.  The patellar tendon avulses a portion of the distal bony patella, along with the retinaculum and articular cartilage from the inferior pole of the patella.  It is common in children between ages 8 and 10 years.  Anatomic reduction and repair of the extensor mechanism are mandatory to reestablish full knee extension.
REFERENCES: Houghton GR, Ackroyd CE: Sleeve fractures of the patella in children: A report of three cases.  J Bone Joint Surg Br 1979;61:165-168.
Wu CD, Huang SC, Liu TK: Sleeve fracture of the patella in children: A report of five cases.  Am J Sports Med 1991;19:525-528.

Question 12

What is the primary mechanism by which anabolic steroids increase muscle tissue? Review Topic





Explanation

Anabolic steroids have many effects on the body. Increased muscle mass occurs specifically through increased production of messenger RNA. HDL levels usually decrease but do not affect muscle. Also, steroids act to change the effects of cortisol to decrease catabolism.

Question 13

A 62-year-old active man returns for routine follow-up 16 years after hip replacement. He has no hip pain. Radiographs  reveal  a  well-circumscribed  osteolytic  lesion  around  a  single  acetabular  screw.  All  hip components are perfectly positioned. Comparison radiographs obtained 6 months later show an increase in the size of the osteolytic lesion. CT depicts a well-described lesion that is 3 cm at its largest diameter and is localized around one screw hole with an eccentric femoral head. What treatment is appropriate, assuming that well-fixed cementless total hip components are in place?




Explanation

DISCUSSION:
Given a well-fixed acetabular metal shell and a localized osteolytic lesion, good outcomes can be expected from liner revision in this clinical scenario with retention of the metal socket, assuming no damage to the components or other unexpected findings arise during revision surgery. Here, complete cup revision is not  warranted,  considering  the  appropriate  implant  position.  Beaulé  and  associates  reviewed  83 consecutive  patients  (90  hips)  in  whom a  well-fixed  acetabular  component  was  retained  in  a  clinical scenario such as the one described. No hip showed recurrence or expansion of periacetabular osteolytic lesions. If the metal cup is unstable, acetabular component revision may be indicated.

Question 14

A 16-year-old female swimmer reports several episodes of atraumatic glenohumeral instability that occur with different arm positions. Examination reveals generalized ligamentous laxity and a positive sulcus sign, and her shoulder can be subluxated both anteriorly and posteriorly. Initial management should consist of





Explanation

DISCUSSION: The patient has multidirectional instability (MDI).  It has been reported that a high percentage of patients with MDI respond to a properly structured exercise program that is continued for at least 3 to 6 months.  If nonsurgical management fails to provide relief, stabilization with an inferior capsular shift procedure has been effective in a high percentage of patients.  Unidirectional repairs, such as the Putti-Platt procedure, are unsuitable for correcting MDI.  Thermal capsulorrhaphy has been reported to have a very high failure rate

(greater than 50%) for treating MDI.

REFERENCES: Burkhead WZ Jr, Rockwood CA Jr: Treatment of instability of the shoulder with an exercise program.  J Bone Joint Surg Am 1992;74:890-896.
Neer CS II, Foster CR: Inferior capsular shift for involuntary inferior and multidirectional instability of the shoulder: A preliminary report.  J Bone Joint Surg Am 1980;62:897-908.
Pollock RG, Owens JM, Flatow EL, et al: Operative results of the inferior capsular shift procedure for multidirectional instability of the shoulder.  J Bone Joint Surg Am

2000;82:919-928.

Miniaci A, Birnie J: Thermal capsular shrinkage for treatment of multidirectional instability of the shoulder.  J Bone Joint Surg Am 2003;85:2283-2287.

Question 15

Figure 38 shows the radiograph of a 75-year-old woman who has had right shoulder pain, difficulty sleeping on the affected arm, and difficulties performing activities of daily living for the past 6 weeks. Initial nonsurgical management includes analgesics, a subacromial cortisone injection, and gentle range-of-motion exercises. However, these modalities have failed to provide relief, and the patient reports that she is unable to elevate her arm. Her pain is worse and she would like the most reliable treatment method for pain relief and functional improvement. What is the best surgical treatment? Review Topic





Explanation

The authors of several studies conducted in Europe have reported promising results in the short- and medium-term with use of a reversed or inverted shoulder implant. The most recent investigation, a multicenter study in Europe in which 77 patients (80 shoulders) with glenohumeral osteoarthritis and a massive rupture of the rotator cuff were treated with the Delta III prosthesis, described an improvement in the mean constant score of 42 points, an increase of 65 degrees in forward elevation, and minimal or no pain in 96% of the patients. Hemiarthroplasty, the “nonconstrained”
option, has long been the standard of care for rotator cuff tear arthropathy. However, careful examination of the literature reveals that the results have not been uniform.

Question 16

This reporting avoids a ceiling and floor effect, where most of the respondents score either at the top or the bottom of the assessment scale.




Explanation

Which of the following statistical tools is used to determine responsiveness?
The only accurate statement is that, at 1 month, patients in group 3 are more likely to live longer than patients in group 1 and 2.
The Kaplan-Meier curve is a statistical method used in survivorship analysis to estimate survival rates at different time points. The horizontal axis depicts the time points and the vertical axis depicts the probability of survival. At a given time point, greater survivorship is demonstrated by higher values on the vertical axis.
Kocher et al. reviewed clinical epidemiology and biostatistics relevant in orthopaedic
surgery. They reported that survivorship data are typically analyzed with use of the Kaplan-Meier method. This analysis is used when the actual date of the end point is known. A survivorship curve can be plotted to illustrate the percentage of patients still alive after the intervention.
Petrie et al. reviewed statistics, terminology and the principles involved in simple data analysis, and outlines areas of medical statistics that have gained
prominence in recent years in orthopaedic papers. The authors provide an insight into some of the more common errors that occur in published orthopaedic journals and which are frequently encountered at the review stage in papers submitted to the Journal of Bone and Joint Surgery.
Figure A depicts a Kaplan-Meier curve for 3 groups of patients undergoing 3 different interventions.
Incorrect Answers:
When evaluating patient-reported outcomes in spine surgery, the Patient- Reported Outcomes Measurement Information System (PROMIS) has been found to have what differences compared to other assessment tools?
Communication failures have been associated with increased treatment costs, increased complications, and delays in patient care.
The leading cause of medical errors, wrong-site surgeries, diagnostic delays and loss to follow-up is attributed to communication errors. Studies have shown that this directly leads to increased complications, increased treatment costs, and delays in patient care. In the surgical setting, the performance of the pre-surgical time-out affords clarification of the treatment plan, confirmation of the procedure and site, and an opportunity for the team to address any concerns.
Weller et al. reviewed barriers to effective teamwork in healthcare delivery. They found that effective communication across all team members, inclusive training, and the creation of democratic teams can reduce treatment delays and minimize complications. They concluded that all team members should have a shared understanding of the situation when involved in patients care.
Lingard et al. performed a prospective study determining the feasibility of a preoperative 10-item checklist discussion including nurses, surgeons, and anesthesiologists. They reported that the discussion usually took place prior to bringing the patient to the OR and took on average 3.5 minuted. Overall, the guided discussion was very well received by participants and provided an opportunity to inform providers of the patient's information to address potential problems. The authors cited that variations in workflow patterns as a potential barrier to widescale implementation of the checklist discussion.
Incorrect answers:
The outcomes of three novel interventions are investigated and the preliminary results are depicted in Figure A. Which of the following statements is most accurate?
Linezolid acts to inhibit protein synthesis by preventing the formation of the initiation complex between the 30S and 50S subunits of the ribosome.
Linezolid is a type of oxazolidinone, a relatively newer class of antibiotics that are active against multidrug-resistant staphylococci, streptococci, and enterococci. Although many antimicrobial agents affect or disrupt protein synthesis in bacteria, linezolid is unique in that it disrupts protein synthesis at its origin rather than later in the cascade. It achieves this by binding to the
50S subunit of the bacterial ribosome, preventing the formation of the initiation complex.
Swaney et al. performed a study to investigate the mechanism of action of linezolid. They found that linezolid inhibits the formation of the initiation complex in bacterial translation systems by preventing the formation of the N- formylmethionyl-tRNA-ribosome-mRNA ternary complex.
Thompson et al. performed a study on the efficacy of various antibiotics in treating periprosthetic joint infections (PJI). They administered oral linezolid with or without oral rifampin, intravenous vancomycin with oral rifampin, intravenous daptomycin or ceftaroline with or without oral rifampin, oral doxycycline, or sham treatment at human- exposure doses for 6 weeks in a mouse model of PJI. They found that oral-only linezolid-rifampin and all intravenous antibiotic-rifampin combinations resulted in no recoverable bacteria and minimized reactive bone changes. Additionally, although oral linezolid was found to be the most effective monotherapy, all oral and intravenous antibiotic monotherapies failed to clear infection or prevent reactive bone changes.
They concluded that the oral-only linezolid-rifampin option might reduce venous access complications and health-care costs.
Illustration A is a diagram depicting the mechanism of action of various antibiotics.
Incorrect Answers:
50S subunit of the bacterial ribosome, preventing protein chain elongation by inhibiting peptidyl transferase activity of the ribosome.
elongation by blocking aminoacyl translocation.
Failure of effective communication in the surgical setting has been associated with what?
Unfractionated heparin works in the coagulation cascade by promoting the ability of antithrombin III to inhibit factors IIa, III, Xa.
Heparin works by binding to and enhancing the ability of antithrombin III to inhibit factors IIa, III, Xa. It is metabolized by the liver. The risks associated with the use of unfractionated heparin include bleeding and heparin induced thrombocytopenia (HIT). The reversal agent is protamine sulfate.
Agnelli et al. reviewed direct thrombin inhibitors for the prevention of VTE after major orthopaedic surgery. They reported widespread use, however, limitations in the use of unfractionated heparin and low-molecular-weight heparins. They highlighted that direct thrombin inhibitors (Ximelagatran) inactivate thrombin without requiring any plasma cofactor, inhibit both free
and fibrin-bound thrombin, and do not appreciably bind to plasma proteins. They concluded that the features of rapid absorption, conversion, bioavailability, low variability, dose-time, food independency, and the predictable anticoagulant activity make direct thrombin inhibitors an attractive antithrombotic agent especially for prolonged out-of hospital prophylaxis.
Kwong et al. reviewed the efficacy and safety of fondaparinux, a selective factor Xa inhibitor and reported its efficacy and safety in 4 phase III clinical trials. They reported fondaparinux usage resulted in an overall 55% decrease in the risk of venous thromboembolism (VTE) relative to the low-molecular- weight heparin enoxaparin without increasing the incidence of clinically relevant bleeding, which was similarly low for both agents. They concluded
that the superior efficacy of fondaparinux relative to enoxaparin is the result of its unique mechanism of action, clinical pharmacology.
McLynn et al. investigated the risk factors and chemoprophylaxis for VTE in elective spine surgery. They reported that independent risk factors for VTE included greater age, male gender, increasing body mass index, dependent functional status, lumbar spine surgery, longer operative time, perioperative blood transfusion, longer length of stay, and other postoperative
complications. The majority of patients received unfractioned heparin and they observed this did not significantly influence the rate of VTE, but was associated with a significant increase in hematoma requiring a return to the operating room. They concluded that there is insufficient evidence to support the routine use of chemoprophylaxis in low-risk patients, and recommended full consideration of risks and benefits after elective spine surgery.
Figure A depicts the coagulation cascade, with the factor circled in red (IIa) being the target of unfractionated heparin, through its effect on antithrombin III.
Incorrect Answers:
Which of the following antibiotics acts to inhibit protein synthesis by preventing the formation of the initiation complex between the 30S and 50S subunits of the ribosome?
Acetaminophen inhibits prostaglandin E2 production through its effect on interleukin-1 beta. It exerts its effects on the central nervous system.
Multimodal pain management has become an increasingly important consideration in total joint arthroplasty recovery, namely in regard to minimizing opioid requirements while optimizing pain control and patient satisfaction. Given the negative side effects and increasing scrutiny on narcotic use, modalities that help to decrease post-operative narcotic requirements have become a major focus and include nonsteroidal anti- inflammatories, selective COX-2 inhibitors, gabapentinoids, local anesthetic blocks, and acetaminophen. Acetaminophen acts directly the central nervous system, providing both pain relief and antipyretic effects. It does so by inhibiting prostaglandin E2 production through the blockade of interleukin-1 beta.
Jinnah et al. performed a comparison of two multimodal pain regimens used for postoperative pain control in total joint arthroplasty patients. They hypothesized that using a multimodal pain protocol focusing on periarticular injections including liposomal bupivacaine would have improved results when compared with a parenteral opioid- based regimen. They found a decrease in length of stay and rate of discharge to skilled nursing facilities with the implementation of a novel multimodal protocol. They concluded that a multimodal approach inclusive of periarticular injection can lead to a reduced
length of stay.
Politi et al. performed a prospective randomized trial comparing the use of intravenous versus oral acetaminophen in total joint arthroplasty. They found that IV acetaminophen did not provide a significant difference in pain relief except within the first 0-4 hours. They concluded that IV acetaminophen does not provide a significant benefit when compared to the oral form, which is also less expensive.
Incorrect Answers:
Which of the following agents results in blood anticoagulation by exerting inhibitory effects on the factor circled in the color red in Figure A?
Based on the stress-strain curve in Figure A, ceramic has the highest modulus of elasticity.
Young's modulus is a measure of the stiffness (ability to resist deformation) of a material in the elastic zone that is calculated by measuring the slope of the stress-strain curve in the elastic zone. A higher modulus of elasticity indicates a stiffer material. Relative values of Young's modulus include: (1) ceramic, (2) alloy, (3) stainless steel, (4) titanium, (5)
cortical bone, (6) matrix polymers, (7) PMMA, (8) polyethylene, (9) cancellous bone, (10) tendon/ligaments, and (11) cartilage.
Lang et al. published a review on the use of ceramics in total hip replacement. They report that properties of ceramic which make it particularly attractive for this application include its hardness, high compression strength, and excellent wettability. However, its low fracture toughness and linear elastic behavior make it prone to breakage under stress.
Figure A is a stress-strain curve, the slope of which is used to determine Young's modulus.
Incorrect Answers:
Which of the following medications work by inhibiting prostaglandin E2 production through interleukin-1 beta?
A power analysis determines the minimum number of patients needed in a study to show a clinically significant difference. It should be performed before starting the study.
Power is the probability of finding a significant association if one truly exists. It is defined as 1 minus the probability of a type 2 error (beta) and is generally set to 80% meaning that we are willing to accept a 20% chance of a type 2 error. A power analysis will determine the minimum number of patients that shows a clinically significant difference. The minimum number of patients should be determined prior to initiating a study. Calculation of power after a study has been completed is controversial and discouraged.
Vavken et al. performed a review on the management of confounding in controlled orthopaedic trials. They report that confounding occurs when the effect of exposure of an outcome is distorted by a confounding factor and will lead to spurious effect estimates in clinical studies. They performed a cross- sectional study of a sample of controlled trials reported in the orthopaedic literature in 2006. They conclude that only 30 studies reported that the had a power analysis performed.
Kocher et al. performed a review of clinical epidemiology and biostatistics as a primer for orthopedic surgeons. They report that a power analysis should be performed prior to initiating the study. This will ensure the study is appropriately powered and decrease the effects of chance. They conclude that when a study determines no significant effect the power of the study should be reported.
Incorrect Answers:
Based on the stress-strain curve in Figure A, which of the following materials has the highest modulus of elasticity?
The World Health Organization (WHO) defines osteopenia as a bone mineral density (BMD) that is between 1 and 2.5 standard deviations below young normal (T-score of - 1 to -2.5).
The WHO defines osteopenia as decreased BMD without fracture risk. Osteopenia is defined as a T-score of 1 to 2.5 standard deviations below young normals (-1 to -2.5), while osteoporosis is defined as a T-score of more than

Question 17

A 66-year-old woman who requires a cane for ambulation now notes increasing difficulty in using the cane after undergoing total elbow arthroplasty 3 months ago. AP and lateral radiographs are shown in Figures 15a and 15b. What is the most likely diagnosis?





Explanation

DISCUSSION: The lateral radiograph reveals a triceps avulsion with a small portion of bone.  Triceps weakness and insufficiency can be a symptomatic problem after total elbow arthroplasty and is probably underreported.  Ulnar nerve neuritis, aseptic loosening, instability, and infection are all complications of total elbow arthroplasty but would not account for the radiographic findings.
REFERENCES: Koval K (ed): Orthopaedic Knowledge Update 7.  Rosemont, IL, American Academy of Orhthopaedic Surgeons, 2002, pp 323-327.
Morrey BF (ed): The Elbow and Its Disorders, ed 3.  Philadelphia, PA, WB Saunders, 2000,

pp 598-601.

Question 18

A 43-year-old former professional hockey player reports severe pain in his chest after being checked from the side in a pick-up hockey game. An MRI scan and plain radiographs are shown in Figures 25a through 25c. What is the most likely diagnosis?





Explanation

DISCUSSION: Anterior dislocation is the most common type of sternoclavicular dislocation.  The medial end of the clavicle is displaced anterior or anterosuperior to the anterior margin of the sternum.  In a study by Omer, 31% of athletic injuries have been known to cause a dislocation of the sternoclavicular joint.  The serendipity view can show this dislocation, as will CT of the chest.  This view requires the x-ray beam to be aimed at the manubrium with 40 degrees of cephalic tilt.  An anterior sternoclavicular joint dislocation will appear superiorly displaced, while a posterior sternoclavicular joint dislocation is inferiorly displaced on the serendipity view.
REFERENCES: Rockwood CA Jr, Matsen FA III (eds): The Shoulder.  Philadelphia, PA, WB Saunders, 1998, vol 1, pp 566-572.
Omer GE Jr: Osteotomy of the clavicle in surgical reduction of anterior sternoclavicular dislocation.  J Trauma 1967;7:584-590.

Question 19

A 58-year-old African-American female who sustained an injury to her upper arm six months ago presents with persistent arm pain. She was initially treated with splinting, with conversion to fracture bracing. She is neurovascularly intact. An injury radiograph and a current radiograph are shown in Figures A and B respectively. What nutritional or metabolic disturbance is the most likely associated with this patient's diagnosis? Review Topic





Explanation

This patient has sustained a humeral diaphyseal fracture that has gone on to an atrophic nonunion. Vitamin D deficiency is the most likely associated metabolic disturbance.
The incidence of nonunion with non-operative management of humeral shaft injuries ranges from 2-10%. Risk factors include vitamin D deficiency (most common), open fractures, segmental injuries, smoking and obesity. The optimal treatment is compression plating with bone grafting, which has been shown to be superior to intramedullary nailing with bone grafting or compression plating alone.
Ring et al. reviewed factors that contributed to humeral diaphyseal nonunion after fracture bracing. Fractures in the proximal to middle one-third of the shaft or fractures with a spiral/oblique pattern were more likely to go on to nonunion.
Brinker et al. reviewed 37 low-energy fractures that went onto nonunion. These patients were evaluated by clinical endocrinologists for evaluation of metabolic abnormalities. Thirty-one of the 37 patients (84%) had a metabolic issue, with 68% (25 of 37 patients) having Vitamin D deficiency.
Figure A demonstrates a humeral shaft fracture. Figure B demonstrates an atrophic nonunion of the humeral shaft fracture.
Incorrect Answers:

Question 20

Which of the following alternatives to autogenous bone grafting functions through osteoinduction?





Explanation

Allograft bone is one of the most common bone graft substitutes, and is frequently used as a bone graft extender. The sterilization process kills all cells but their three-dimensional structure is retained, offering an osteoconductive scaffold. Tricalcium phosphate, calcium phosphate, and calcium sulfate are also osteoconductive materials with a three-dimensional scaffold similar to native cancellous bone. Bone morphogenetic protein is an inductive protein, which stimulates osteoprogenitor cells to differentiate along a bone-forming lineage.

Question 21

An 18-year-old man underwent open reduction and internal fixation of a tibial spine avulsion and a posterolateral corner repair. Two years later, he underwent lateral collateral ligament (LCL) and posterolateral corner reconstruction because of instability. Examination reveals a pronounced lateral varus knee thrust when ambulating. Varus stress in 30 degrees of flexion produces a 10-mm opening that is eliminated in extension. The Lachman’s test is 2 mm with a firm end point, and the posterior drawer test is negative. Standing radiographs show widening of the lateral joint space and a 5-degree mechanical varus alignment. What is the most effective course of treatment?





Explanation

DISCUSSION: The patient has chronic posterolateral instability with a varus knee alignment; therefore, the most effective treatment is a valgus-producing HTO.  A repeat soft-tissue reconstruction without correction of the varus alignment will most likely fail.  An ACL reconstruction is not indicated with a normal Lachman’s test.  Physical therapy and bracing will have little effect.
REFERENCES: Naudie DD, Amendola A, Fowler PJ: Opening wedge high tibial osteotomy for symptomatic hyperextension-varus thrust.  Am J Sports Med 2004;32:60-70.
Covey DC: Injuries of the posterolateral corner of the knee.  J Bone Joint Surg Am
2001;83:106-118.

Question 22

During the anterior approach for repair of a distal biceps tendon rupture, what structure, shown under the scissors in Figure 6, is at risk for injury?





Explanation

DISCUSSION: The most commonly injured neurovascular structure during an anterior approach for the repair of a distal biceps tendon rupture is the lateral antebrachial cutaneous nerve.  This structure is located lateral to the biceps tendon and in a superficial location just deep to the subcutaneous layer.  The antecubital vein is medial and superficial with the brachial artery and median nerve also medial to the biceps tendon but deep to the common flexors.  The posterior interosseous nerve is deep within the supinator muscle and can be injured in the deep dissection or through the posterior approach when using a two-incision approach.
REFERENCES: Kelly EW, Morrey BF, O’Driscoll SW: Complications of repair of the distal biceps tendon with the modified two-incision technique.  J Bone Joint Surg Am 2000;82:1575-1581.
Ramsey ML: Distal biceps tendon injuries: Diagnosis and management.  J Am Acad Orthop Surg 1999;7:199-207.

Question 23

A biopsy of the involved physis in a patient with slipped capital femoral epiphysis (SCFE) would most likely reveal





Explanation

DISCUSSION: Vascular invasion, histologically similar to granulation tissue, has been noted between the columns in the zone of hypertrophy, leading to the theory of microtrauma as an etiology.  SCFE is also associated with conditions that increase the height of the zone of hypertrophy, including the adolescent growth spurt and endocrinopathies.   The perichondral ring has been shown to decrease in thickness with age.  Normal undulations in the growth plate also decrease during this time, possibly further destabilizing the physis.  Abnormal accumulations of proteoglycan have been reported.
REFERENCES: Chung SM, Batterman SC, Brighton CT: Shear strength of the human femoral capital epiphyseal plate.  J Bone Joint Surg Am 1976;58:94-103.  
Raney EM, Ogden JA: Slipped capital femoral epiphysis.  Current Ortho 1995;9:111-116.

Question 24

Which of the following findings is a contraindication to isolated percutaneous pinning of a distal radius fracture?





Explanation

DISCUSSION: Intrafocal pinning allows the Kirschner wires to be placed through a site of comminution and then drilled through intact cortex.  Generally Kapandji intrafocal pinning is done for dorsal comminuted extra-articular dorsal bending fractures, but it also may be used to elevate and buttress radial comminution.  Simple intra-articular fractures can also be treated with pinning alone.  Intrafocal pinning works best as a dorsal or radial buttress to prevent shortening.  When there is volar comminution, the fracture is prone to shortening and supplemental external fixation or plating is recommended.
REFERENCES: Trumble TE, Wagner W, Hanel DP, et al: Intrafocal (Kapandji) pinning of distal radius fractures with and without external fixation.  J Hand Surg Am 1998;23:381-394.
Choi KY, Chan WS, Lam TP, et al: Percutaneous Kirschner-wire pinning for severely displaced distal radial fractures in children: A report of 157 cases.  J Bone Joint Surg Br 1995;77:797-801.
Weil WM, Trumble TE: Treatment of distal radius fractures with intrafocal (Kapandji) pinning and supplemental skeletal stabilization.  Hand Clin 2005;21:317-328.

Question 25

Which radiographic abnormality most accurately serves as a predictor of ankle syndesmosis disruption?




Explanation

DISCUSSION
Normal syndesmotic relationships include a tibiofibular clear space smaller than 6 mm on both AP and mortise views. In a 1989 cadaveric study by Harper and Keller, a tibiofibular clear space exceeding 6 mm on both the AP and mortise views was the most reliable predictor of early syndesmotic widening. Tibiofibular overlap is measured 1 cm proximal to the plafond. Normal values exceed 6 mm or 42% of the width of the fibula on the AP view, or 1 mm on the mortise view. Proximal fibula fracture can occur in isolation without syndesmotic injury, frequently after direct trauma. The medial clear space is the distance between the lateral border of the medial malleolus and the medial border of the talus and is measured at the level of the talar dome. In the mortise view with the ankle in neutral dorsiflexion, the medial clear space should be equal to or smaller than the superior clear space between the talar dome and the tibial plafond. ?A normal medial clear space may be present with syndesmotic injury and consequently lacks sensitivity and specificity.
RECOMMENDED READINGS
Zalavras C, Thordarson D. Ankle syndesmotic injury. J Am Acad Orthop Surg. 2007 Jun;15(6):330-9. Review. PubMed PMID: 17548882. View Abstract at PubMed
Wuest TK. Injuries to the Distal Lower Extremity Syndesmosis. J Am Acad Orthop Surg. 1997 May;5(3):172-181. PubMed PMID: 10797219. View Abstract at PubMed
Harper MC, Keller TS. A radiographic evaluation of the tibiofibular syndesmosis. Foot Ankle. 1989 Dec;10(3):156-60. PubMed PMID: 2613128. View Abstract at PubMed
CLINICAL SITUATION FOR QUESTIONS 37 THROUGH 40
A 41-year-old man sustained a twisting injury while running up stairs 4 weeks ago. He was treated in an ankle brace and has been bearing weight since the injury occurred. He has no history of ankle problems, but he now has ankle pain, swelling, and instability. The pain is aggravated by stairs, and the instability is worse on unlevel ground. Radiographs do not show a fracture.

Question 26

Treatment of adhesive capsulitis has a high failure rate when the underlying cause is





Explanation

DISCUSSION: Diabetes mellitus has been associated with resistant cases of adhesive capsulitis.  With other causes of onset, adhesive capsulitis frequently responds to nonsurgical management such as stretching exercises or, when this fails, manipulation under anesthesia and/or arthroscopic release.  Manipulation is rarely successful for the treatment of adhesive capsulitis associated with diabetes mellitus, and arthroscopic release may be preferred.
REFERENCES: Fisher L, Kurtz A, Shipley M: Association between cheiroarthropathy and frozen shoulder in patients with insulin-dependent diabetes mellitus.  Br J Rheumatol 1986;25:141-146.
Janda DH, Hawkins RJ: Shoulder manipulation in patients with adhesive capsulitis and diabetes mellitus: A clinical note.  J Shoulder Elbow Surg 1993;2:36-38.
Pollock RG, Duralde XA, Flatow EL, Bigliani LU: The use of arthroscopy in the treatment of resistant frozen shoulder.  Clin Orthop 1994;304:30-36.

Question 27

A 49-year-old woman noted pain in her right axilla 1 day after moving heavy furniture. Two weeks later, she now reports persistent numbness and paresthesias along the inner aspect of her upper arm radiating into the ulnar digits. Examination reveals full shoulder motion, tenderness over the first rib, and a decreased radial pulse with the shoulder placed overhead. What is the most likely diagnosis?





Explanation

DISCUSSION: Thoracic outlet syndrome is thought to be caused by compression of the neurovascular supply to the upper limb in the supraclavicular and axillary regions of the shoulder.  While typically progressive in onset, thoracic outlet syndrome may develop after acute injury.  Injury or weakness of the scapular muscles, especially the trapezius, may result in descent of the scapula and cause compression of the thoracic outlet.  In general, most symptoms are the result of neural compression.  Typical symptoms include pain in the neck or shoulder and numbness or tingling that predominantly involves the ulnar side of the arm and hand.  Exacerbation of these symptoms is typical when the arm is abducted.  Initial management should consist of postural exercises aimed at restoring proper scapular stability.  Severe recalcitrant symptoms may warrant surgical decompression.
REFERENCES: Leffert RD: Thoracic outlet syndrome.  J Am Acad Orthop Surg 1994;2:317-325.
Todd TW: The descent of the shoulder after birth: Its significance in the production of pressure-symptoms on the lowest brachial trunk.  Anat Anz 1912;41:385-397.

Question 28

-The use of a soft cervical orthosis is most supported for which injury?





Explanation

Question 29

Figure 19 shows an arthroscopic view from the anterior lateral portal of the knee looking into the suprapatella pouch. The use of an electrothermal device during this procedure most commonly causes significant postoperative complications by damaging which of the following structures?





Explanation

DISCUSSION: While it is possible to damage any of these structures, unrecognized intraoperative laceration without adequate coagulation of the superior lateral geniculate artery is common.  This can result in significant postoperative hemarthrosis and a return to surgery when bleeding cannot be controlled.
REFERENCES: Cash JD, Hughston JC: Treatment of acute patella dislocation.  Am J Sports Med 1988;16:244-249.
Henry R, Goletz B, Williamson C: Lateral release in patello-femoral subluxation.  Am J Sports Med 1986;14:121.

Question 30

In patient selection for meniscal allograft transplantation, which of the following variables has the greatest influence on outcome?





Explanation

DISCUSSION: Many clinical studies to date show that the extent of arthritis is the most common variable that has the greatest influence on outcome.  The success rate of allograft transplantation is significantly diminished in patients who have grade IV chondromalacia of the knee or notable flattening and general joint incongruity.
REFERENCES: Carter TR: Meniscal allograft transplantation.  Sports Med Arthroscopy Rev 1999;7:51-63.
Garrett JC: Meniscal transplantation: A review of 43 cases with two- to seven-year follow-up.  Sports Med Arthroscopy Rev 1993;2:164-167.
van Arkel ER, de Boer HH: Human meniscal transplantation: Preliminary results at 2- to 5-year follow-up.  J Bone Joint Surg Br 1995;77:589-595.

Question 31

A 30-year-old patient has acetabular dysplasia and moderate secondary osteoarthrosis. Which of the following studies will best help predict the success of periacetabular osteotomy?





Explanation

DISCUSSION: Improvement in the appearance of the hip joint on functional radiographic evaluation (abduction/adduction views) has been shown to be predictive of outcome following joint preserving surgery.  CT and MRI findings have not been shown to be predictive of outcome. 
REFERENCE: Murphy S, Deshmukh R: Periacetabular osteotomy: Preoperative radiographic predictors of outcome. Clin Orthop 2002;405:168-174.

Question 32

Because the patient shown in Figure 27 can no longer fit in shoes, treatment of the deformity should consist of





Explanation

DISCUSSION: In local gigantism, a ray resection allows proper fitting of shoes.  The ray resection narrows the foot and shortens the length.  The foot may require further surgery with growth.  Debulking, physeal arrest, and distal phalanx amputation are unlikely to be effective. 
REFERENCES: Turra S, Santini S, Cagnoni G, Jacopetti T: Gigantism of the foot: Our experience in seven cases. J Pediatr Orthop 1998;18:337-345. 
Guidera KJ, Brinker MR, Kousseff BG, et al: Overgrowth management in Klippel-Trenaunay-Weber and Proteus syndromes.  J Pediatr Orthop 1993;13:459-466. 

Question 33

-What is the most likely area of injury?




Explanation

DISCUSSION FOR QUESTIONS 40 THROUGH 42
This patient likely has a physeal injury to the distal femoral physis. Stress radiographs or an MRI scan will most reliably reveal this diagnosis. The growth plate, when injured, is most commonly fractured through the hypertrophic zone of cartilage, its weakest point. This patient is optimally treated in a cylindrical or long-leg cast. Younger patients can be treated with a hip spica with a leg extension.

Question 34

Arthritic change in cartilage is characterized by which of the following findings?





Explanation

Experimental models of late-stage arthritis in animals demonstrated lower compressive modulus, higher permeability, and higher water content. There is proteoglycan loss within the matrix. A significant and progressive decrease in the tensile and shear modulus has been observed.

Question 35

A diskectomy is performed in which the disk space is not aggressively debrided. When compared to techniques that involve aggressive debridement of the disk space, this results in




Explanation

DISCUSSION
This patient has disk herniation at the left L5-S1 level. This will generally affect the traversing S1 nerve. The S1 dermatome is on the lateral aspect and sole of the foot.
Surgical treatment generally involves a diskectomy with removal of the herniated fragment. This can be performed via a conventional open approach or minimally invasive endoscopic technique. Several recent meta-analyses have demonstrated equivalent outcomes with regard to leg pain and clinical outcomes. Although minimally invasive techniques have been associated with an increased rate of dural tear, the overall complication rate between the 2 techniques is not significantly different. Several studies have demonstrated a substantial learning curve associated with minimally invasive techniques, and the rate of complications decreases significantly with surgeon experience.
When performing a diskectomy, the herniated fragment alone can be removed (sequestrectomy) or some of the disk that remains in the disk space can be removed (complete diskectomy). Studies have shown no change in surgical time, blood loss, length of stay, or surgical complications when performing a sequestrectomy (compared to a more complete diskectomy). A sequestrectomy is associated with a higher rate of recurrent disk herniation at the surgical level.
RECOMMENDED READINGS
Kamper SJ, Ostelo RW, Rubinstein SM, Nellensteijn JM, Peul WC, Arts MP, van Tulder MW. Minimally invasive surgery for lumbar disc herniation: a systematic review and meta-analysis.
Eur Spine J. 2014 May;23(5):1021-43. doi: 10.1007/s00586-013-3161-2. Epub 2014 Jan 18.
PubMed PMID: 24442183. View Abstract at PubMed
Dasenbrock HH, Juraschek SP, Schultz LR, Witham TF, Sciubba DM, Wolinsky JP, Gokaslan ZL, Bydon A. The efficacy of minimally invasive discectomy compared with open discectomy: a meta-analysis of prospective randomized controlled trials. J Neurosurg Spine. 2012 May;16(5):452-62. doi: 10.3171/2012.1.SPINE11404. Epub 2012 Mar 9. PubMed PMID:

Question 36

A 28-year-old construction worker sustains the closed injury shown in Figures A and B after a fall from a height. He is taken to the operating room. What is the next best step?





Explanation

This patient has an extraarticular distal tibia fracture and distal fibula fracture. Reamed intramedullary nailing and fibular plating is indicated in this case.
In the distal tibial metaphysis, there is no snug endosteal fit for an IM nail. Center-center nail placement in both proximal and distal fragments is necessary to maintain alignment. There is also increased stress on distal locking bolts to maintain fracture alignment. Assuming static medial-lateral distal locking screws, accurate coronal plane and rotational alignment is achieved by fibular plating as a first step. This also
prevents late loss of alignment because of distal locking screw toggle. Reamed nailing allows a stiffer, larger nail to be placed, and allows redistribution of endosteal osteogenic material to the fracture site. Although there is endosteal vascular compromise, this does not affect fracture healing because of intact periosteal supply.
Bhandari et al. conducted a prospective, randomized, blinded comparison of 622 patients who had reamed nailing, and 604 who had unreamed nailing. For closed fractures, a significantly greater number in the unreamed group required bone grafting, implant exchange and dynamization. There was no difference in groups for open fracture nailing.
Egol et al. retrospectively reviewed distal metaphyseal tibia-fibula fractures treated with IM nailing with (25 cases) and without (47 cases) adjunctive plating. They found that plating was associated with maintenance of reduction (significant) as was the use of 2 medial-lateral distal locking bolts (not significant). They recommend fibular plating when IM nailing for distal tibia fractures.
Figures A and B show an extraarticular distal tibia fracture with distal fibula fracture. Incorrect Answers

Question 37

What adaptations occur in the dominant shoulder of throwers compared to their nondominant shoulder? Review Topic





Explanation

Pitchers change rotation during adolescent growth with external rotation of the proximal humerus. The result is increased external rotation and decreased internal rotation, resulting in a normal total arc of motion. External rotation lengthens the arc of acceleration, resulting in increased velocity. The shorter arc of internal rotation, associated with a tight posterior capsule, makes deceleration of the arm more difficult, which may lead to overuse injuries.

Question 38

A 42-year-old woman who has had an 18-month history of severe low back pain is referred to your office for surgical evaluation. She reports that the pain initially began with right lower extremity pain and management consisted of oral analgesics, nonsteroidal anti-inflammatory drugs, and muscle relaxants. She has seen a chiropractor as well as a pain management specialist and she is status-post epidural steroid injections. She has also completed exhaustive physical therapy, as she is a certified athletic trainer and runs a health fitness program at a community hospital. Currently, she denies lower extremity pain and her pain is isolated to her low back and is subjectively graded as 8/10, with 10 being the worst pain she has ever experienced. The pain is interfering with her activities of daily living and she is seeking definitive treatment. Figures 32a through 32c show current MRI scans. Based on the current available medical literature, what is the most appropriate treatment? Review Topic





Explanation

The MRI scans reveal advanced degenerative disk disease at L5-S1. Nonsurgical management has failed to provide relief and the patient is quite debilitated as a result of her back pain. Fritzell and associates demonstrated that in a well-informed and selected group of patients with severe low back pain, lumbar fusion can diminish pain and decrease disability more efficiently than commonly used nonsurgical treatments.
In a recent updated Cochrane Review of surgery for degenerative lumbar spondylosis, it was noted that while Fritzell and associates appeared to provide strong evidence in favor of fusion, a more recent trial by Brox and associates demonstrated no difference between those patients undergoing lumbar fusion compared to those receiving cognitive intervention and exercise. The Cochrane Review suggests that this may reflect a difference between the control groups. Fritzell and associates compared lumbar fusion to standard 1990s “usual care,” whereas Brox and associates compared lumbar fusion to a “modern rehabilitation program.” Bear in mind that this patient is a certified athletic trainer and runs a hospital health fitness department; therefore, at least for purposes of this question, it can be assumed that she has participated in a “modern rehabilitation program.” The Cochrane Review goes on to state that preliminary results of three small trials of intradiskal electrotherapy suggest that it is ineffective and that preliminary data from three trials of disk arthroplasty do not permit firm conclusions.

Question 39

  • For which of the following conditions will a rehabilitation program for shoulder instability most likely result in a satisfactory response?





Explanation

In a study by Burkhead and Rockwood, shoulder instability was classified with criteria applying to whether a patient had traumatic or atraumatic subluxation of the
glenohumeral joint. In this classification Type I is a traumatic subluxation without previous dislocation, Type II is a traumatic subluxation after previous dislocation, Type IIIA is an atraumatic, voluntary subluxation in patients with psychological problems, Type IIIB is and atraumatic, voluntary subluxation in a patient without psychological problems and Type IV is an involuntary subluxation. In their study they found that
shoulders that have traumatic instability (type I or type II) had a 15 per cent chance of a good or excellent outcome with a rehab program as compared with atraumatic subluxations (type III or type IV) which had an 83 per cent good to excellent result. Since answer 5 is the only atraumatic type of subluxation it would statistically stand the best chance for improvement with a rehab program.

Question 40

A 47-year-old male tennis player has pain in his nondominant shoulder that has failed to respond to 4 months of nonsurgical management. Examination reveals acromial tenderness and pain at the supraspinatus tendon insertion. He has a positive impingement sign, pain on forward elevation, and minimal cuff weakness. The MRI scans are shown in Figures 30a and 30b. To completely resolve his symptoms, treatment should consist of





Explanation

DISCUSSION: The MRI scans show a mesoacromion with tendonopathy of the supraspinatus.  The history and physical findings indicate that the patient has a symptomatic os acromiale.  Simple excision of the unstable os acromiale has not yielded consistently good results.  Meticulous internal fixation using tension banding with cannulated screws and autologous bone grafting has shown good results for this problem.
REFERENCES: Hutchinson MR, Veenstra MA: Arthroscopic decompression of shoulder impingement secondary to os acromiale.  Arthroscopy 1993;9:28-32.
Warner JJ, Beim GM, Higgins L: The treatment of symptomatic os acromiale.  J Bone Joint Surg Am 1998;80:1320-1326.

Question 41

An 18-year-old male soccer player sustains a knee injury during a game. Examination is notable for a positive pivot shift test. What other physical examination finding is most likely to be present? Review Topic





Explanation

The patient has sustained a tear of his anterior cruciate ligament (ACL), as demonstrated by the positive pivot shift test; therefore, he would most likely exhibit lateral joint line tenderness indicative of a lateral meniscus tear, the most common intraarticular injury associated with an ACL tear.
ACL tears usually occur as a result of a non-contact pivoting injury. Abnormal anterior translation results in bone contusions of mid-lateral femoral condyle and posterolateral tibia, which can be seen on MRI. Other concomitant intraarticular injuries include meniscal tears (lateral > medial), chondral damage and other ligamentous injury (MCL, LCL, PLC) usually found in cases of higher energy trauma such as a knee dislocation.
Piasecki et al prospectively analyzed intraarticular injuries associated with ACL tears in high school athletes by gender and sport. There was no significant difference in mechanism of injury between sexes. Female basketball and soccer players had fewer intraarticular injuries (medial femoral condyle lesions, medial and lateral meniscus tears) compared to male athletes. The authors hypothesized that women may therefore enjoy a better prognosis following reconstruction.
Spindler et al performed a prospective cohort study investigating concomitant intraarticular injuries in patients who underwent ACL reconstruction. Eighty percent of patients had a bone bruise on MRI, 68% involving the lateral condyle. At time of arthroscopic reconstruction, meniscal tears were identified in 56% of lateral menisci and 37% of medial menisci.
Incorrect Responses:

Question 42

-What is the etiology of this patient’s problem?




Explanation

DISCUSSION FOR QUESTIONS 78 THROUGH 80
Little leaguer’s shoulder is an overuse condition of the proximal humeral physis. Patients report diffuse pain that is worse with throwing. Factors that contribute to the condition include excessive throwing,improper throwing mechanics, and muscle-tendon imbalance. Radiographs usually show widening of the proximal humeral physis, and, in more severe cases, metaphyseal demineralization or fragmentation. Surgical fixation is not required for healing. Treatment involves rest until symptoms resolve, followed by initiation of an interval throwing program. Pitching coaches should evaluate throwing mechanics and maintain pitch counts. The dominant shoulders of throwing athletes undergo adaptive changes, resulting in increased external rotation and decreased internal rotation. These changes occur secondary to softtissue and bony adaptations, including increased humeral retroversion. Ischemia has been implicated as a potential cause of osteochondritis dissecans lesions. Rotator cuff tendonitis presents with anterolateral shoulder pain that is worse with activity. Pain is reproduced with resisted supraspinatus testing, and radiograph findings are typically normal.
Adolescent shoulder injuries are often caused by subtle, atraumatic instability most often sustained in sports with overhead movements, including baseball. These symptoms are more likely to occur in athletes with evidence of increased soft-tissue laxity.

Question 43

Figure 100 is the MRI scan of a 52-year-old runner who has right knee pain that has been occurring 10 minutes into her run for 2 months. On examination, she has tenderness over the lateral epicondyle. Her Ober test result is positive. What is the most appropriate initial treatment? Review Topic




Explanation

Iliotibial band syndrome (ITBS) is a common cause of lateral knee pain in runners. Potential etiologies for the pain include repetitive friction, compression, and bursal inflammation. An Ober test is used to assess iliotibial band tightness. With the patient lying on the unaffected side, the affected leg is abducted and extended. The test result is positive if the examiner is unable to adduct the leg from this position. An MRI scan can be helpful in making the diagnosis, but a negative MRI scan does not rule out ITBS. Studies have reported increased signal intensity on T2-weighted images deep to the iliotibial band adjacent to the lateral epicondyle, with thickening of the iliotibial band. Nonsurgical treatment is most appropriate initially and involves activity modification, ice, anti-inflammatory medications, and stretching. Corticosteroid injection to the iliotibial bursa is also an option to treat acute pain. After the initial inflammation improves, a strengthening program is started. Multiple surgical procedures have been described for recalcitrant cases, including iliotibial band excision, Z-lengthening, and iliotibial band bursectomy.

Question 44

One year after undergoing a primary total knee arthroplasty, a 65-year-old man has a 1-week history of new onset anterior knee pain. He can perform a straight-leg raise with no extension lag. Radiographs reveal a transverse patella fracture with 8 mm of displacement and an intact patellar component. The best course of treatment is




Explanation

DISCUSSION
This patient has a displaced periprosthetic patella fracture with an intact extensor mechanism. Surgical treatment for this condition has been associated with relatively poor clinical results because the fracture occurs late (attributable to patella osteonecrosis). The optimal initial treatment is to treat the fracture nonsurgically with immobilization of the knee in extension either with a long-leg cast or knee immobilizer.

Question 45

A 17-year-old high school football player is seen for follow-up after sustaining an injury 3 days ago. He reports that he tackled a player, felt numbness throughout his body, and could not move for approximately 15 seconds. A spinal cord injury protocol was initiated on the field. Evaluation in the emergency department revealed a normal neurologic examination and full painless neck motion. He states that he has no history of a similar injury. An MRI scan of the cervical spine is normal. During counseling, the patient and his family should be informed that he has sustained





Explanation

DISCUSSION: The long-term effect of transient quadriplegia is unknown.  Based on a history of one brief episode of transient quadriplegia and normal examination and MRI findings, the risk of permanent spinal cord injury with a return to play is low.  There is a risk of recurrent episodes of transient quadriplegia after the initial episode.
REFERENCES: Morganti C, Sweeney CA, Albanese SA, et al: Return to play after cervical spine injury.  Spine 2001;26:1131-1136.
Odor JM, Watkins RG, Dillin WH, et al: Incidence of cervical spinal stenosis in professional and rookie football players.  Am J Sports Med 1990;18:507-509.
Torg JS, Naranja RJ Jr, Palov H, et al: The relationship of developmental narrowing of the cervical spinal canal to reversible and irreversible injury of the cervical spinal cord in football players.  J Bone Joint Surg Am 1996;78:1308-1314.
Vaccaro AR, Watkins B, Albert TJ, et al: Cervical spine injuries in athletes: Current return-to-play criteria.  Orthopedics 2001;24:699-703.

Question 46

CLINICAL SITUATION Figures 1 through 3 are the radiographs of a 25-year-old man who is brought to the emergency department after a motorcycle collision. He is complaining of isolated knee pain. Examination reveals swelling, popliteal ecchymosis, joint line pain, and limited knee joint motion. His pulses and sensation are normal. Figures 4 through 8 are the axial and coronal CT scan sections of the injury. Intra-operative patient positioning for definitive fixation should be




Explanation

Discussion: Medial plateau fracture dislocations are rare. Failure to recognize this pattern can lead to poor patient outcomes secondary to poor surgical decision making. Pathognomonic findings on the anteroposterior radiograph include an intact lateral column (lateral articular surface still in continuity with tibial shaft), centrolateral articular impaction, shortening, and condylar widening. The medial femoral condyle stays with the fractured medial tibial plateau segment.
Initial management of axially unstable tibial plateau fractures with soft tissue swelling should consist of spanning external fixation and closed manipulative realignment. This allows for soft tissue recovery with the knee joint provisionally stabilized in reduced station. It also provides time for pre-operative planning, which is typically empowered via a CT scan with reconstructions. If the pattern was initially misdiagnosed as a more typically bicondylar tibial plateau fracture, the CT scan will clarify the misconception and allow for better surgical decision making.
Supine positioning is preferred for definitive fixation, but surgical approaches vary. Attempting to stabilize a medial partial articular pattern in the supine position from a lateral utility approach is fraught with difficulties. Lateral locked plating is not designed for this indication. The lateral utility approach allows for visualization of the centrolateral impaction and lateral meniscal peripheral capsular avulsion repair, but when used alone leads to biomechanically unsound implant placement. The primary plate should be on the medial side of the tibia rather than the intact lateral column.

Question 47

Following a fall from a height of 5 feet, a patient reports pain along the lateral border of the foot. The CT scan shown in Figure 54 indicates what pathology?





Explanation

DISCUSSION: The CT scan reveals an avulsion of the dorsal beak of the anterior process of the calcaneus.  This common fracture is an avulsion of the origin of the bifurcate ligament, which runs from the anterior calcaneal process to both the cuboid and the lateral aspect of the navicular.  An inversion mechanism is common, and the fracture is often missed in evaluation for a suspected ankle sprain.  MRI may be useful in the diagnosis of these occult injuries, and suspicion should be present when tenderness exists over the superior portion of the anterior process of the calcaneus.
REFERENCE: Robbins MI, Wilson MG, Sella EJ: MR imaging of anterosuperior calcaneal process fractures.  Am J Roentgenol 1999;172:475-479.

Question 48

A 42-year-old woman complains of ankle pain with weightbearing for the last 2 years. She recalls spraining her ankle more than 10 years ago. She plays tennis and regularly walks 5 miles a day for exercise, but has had to give up these activities over the last few months because of pain. Examination reveals limitation in ankle dorsi- and plantar flexion. A course of non-operative management has been unsuccessful. Which of the following options will most likely provide pain relief and allow her to return to her previous activity level?





Explanation

This young, active patient has ankle valgus following previous trauma. A corrective supramalleolar osteotomy of the tibia will provide pain relief and improve range of motion, allowing return to sports.
Supramalleolar osteotomy may be performed for varus (medial opening wedge or lateral closing wedge) or valgus (lateral opening wedge or medial closing wedge) ankles. They are suited for near-normal ROM minimal talar-tilt or varus heel alignment, asymmetric ankle arthritis (confined to medial or lateral compartment; corresponding to Takakura Stage II or IIIA for medial ankle arthritis).
Pagenstert et al. looked at realignment surgery for posttraumatic arthritis in 35 patients. For valgus ankles, they performed 18 medial closing wedge and 1 lateral opening wedge osteotomies. For varus ankles, they performed 7 medial opening wedge and 4 lateral closing wedge osteotomies. There was improvement in pain (7/10 to 3/10), ROM (33° to 38°) and Takakura score (2.3 to 1.3).
Lee et al. described supramalleolar osteotomy for medial arthritis in 16 patients. There was improvement in AOFAS score (62 to 82), Takakura stage (2.9 to 2.3), tibial-anterior surface angle (85 to 100°). Patients with low postoperative talar tilt (TT) had better clinical and radiographic results than those with high TT. Greater postoperative heel valgus predicted for postoperative subfibular pain.
Figure A shows valgus alignment at the ankle. Illustration A shows the same ankle following medial closing wedge supramalleolar osteotomy. Illustration B is a table showing the Takakura classification. Illustration C demonstrates correction of the tibial-anterior surface angle (TAS) following supramalleolar osteotomy.
Incorrect Answers:

Question 49

  • Which of the following is considered an advantage of an unreamed intramedullary nail over a reamed intramedullary nail?





Explanation

The advantage of an unreamed intramedullary nail is a loose-fitting intramedullary rod. Placed in the medullary canal, it allows the endosteal circulation to regenerate rapidly and completely where space has been left between the nail and the endosteal surface. The endosteal blood vessels are destroyed during introduction of reamed intramedullary nail.

Question 50

A 46-year-old man fell 20 feet and sustained the injury shown in Figure 3. The injury is closed; however, the soft tissues are swollen and ecchymotic with blisters. The most appropriate initial management should consist of





Explanation

DISCUSSION: Although this is a fracture of the medial and lateral malleoli, the degree of displacement and comminution of the medial dome indicate that this injury is similar to a pilon fracture.  Initial management should consistent of stabilization to allow for soft-tissue healing.  The use of temporizing spanning external fixation should be the initial step, followed by limited or more extensive open reduction and internal fixation when the soft-tissue status will allow.  Initial placement in either a short or long leg cast does not provide the needed stability and does not allow for care and monitoring of soft tissues.  In addition, maintaining reduction of the talus may be very difficult.  Immediate open reduction and internal fixation through an injured soft-tissue envelope adds the risk of difficulties with incision healing and a higher risk of deep infection.  In the acute setting, a primary ankle fusion through this soft-tissue envelope is

not indicated.

REFERENCES: Marsh JL, Bonar S, Nepola JV, et al: Use of an articulated external fixator for fractures of the tibial plafond.  J Bone Joint Surg Am 1995;77:1498-1509.
Wyrsch B, McFerran MA, McAndrew M, et al: Operative treatment of fractures of the tibial plafond: A randomized, prospective study.  J Bone Joint Surg Am 1996;78:1646-1657.
Thordarson DB: Complications after treatment of tibial pilon fractures: Prevention and management strategies.  J Am Acad Orthop Surg 2000;8:253-265.

Question 51

A 35-year-old woman reports worsening pain after undergoing a neurectomy in the third interspace for a Morton’s neuroma 12 months ago. She states that the pain is sharp and electrical, worse than before her surgery, and prevents her from participating in her usual work and exercise activities. Use of wider shoes and pads used before her surgery have failed to provide relief. Examination does not reveal any deformity or inflammation. Tenderness along with neuritic pain occurs with compression of the plantar aspect of the foot between the third and fourth metatarsal head area. To most reliably alleviate her pain, management should consist of





Explanation

DISCUSSION: Most patients with a significant recurrent neuroma will not obtain relief with conservative methods.  Pain results from a stump neuroma at the weight-bearing area from too short of a resection of the nerve or from regrowth of the remaining nerve end.  Although steroid injection may be helpful in localizing symptoms or providing temporary relief, it rarely cures a stump neuroma.  Orthotics with a metatarsal pad will likely increase pressure and pain at the neuroma site.  Physical therapy could temporize the symptoms but will not address the underlying problem.  Similarly, bone decompression alone will not alter the location of the neuroma stump.  Revision of the nerve to a more proximal level off of the weight-bearing area is the most likely method to succeed.  A plantar approach facilitates identification and ability to revise the nerve to a more proximal level.
REFERENCES: Mizel MS, Miller RA, Scioli MW (eds): Orthopaedic Knowledge Update: Foot and Ankle 2.  Rosemont, IL, American Academy of Orthopaedic Surgeons, 1998, pp 101-111.
Johnson JE, Johnson KA, Unni KK: Persistent pain after excision of an interdigital neuroma: Results of reoperation.  J Bone Joint Surg Am 1988;70:651-657.
Beskin JL, Baxter DE: Recurrent pain following interdigital neurectomy: A plantar approach.  Foot Ankle 1988;9:34-39.
Amis JA, Siverhus SW, Liwnicz BH: An anatomic basis for recurrence after Morton’s neuroma excision.  Foot Ankle 1992;13:153-156.

Question 52

The recurrent motor branch of the median nerve innervates which of the following muscles?





Explanation

DISCUSSION: The recurrent motor branch of the median nerve supplies the thenar muscles (abductor pollicis brevis, flexor pollicis brevis, and opponens pollicis) that are primarily responsible for thumb opposition.  The nerve can be injured in carpal tunnel release.  A branch of the nerve also supplies the first lumbrical.  The adductor pollicis and the interossei are supplied by the ulnar nerve.
REFERENCES: Last RJ: Anatomy: Regional and Applied, ed 6.  London, England, Churchill Livingstone, 1978, p 109.
Hoppenfeld S, deBoer P: Surgical Exposures in Orthopaedics: The Anatomic Approach.  Philadelphia, PA, JB Lippincott, 1984, p 170.

Question 53

What tendon is closest to an appropriately placed anterolateral portal for ankle arthroscopy?





Explanation

DISCUSSION: The appropriate placement of the anterolateral portal provides access to the lateral gutter of the joint while avoiding the superficial peroneal nerve.  The safest location for the portal is approximately 4 mm lateral to the peroneus tertius tendon, the closest of the tendons listed to the anterolateral portal.  Because the superficial peroneal nerve location is variable, attempts to visualize, palpate, or transilluminate the nerve are mandatory.
REFERENCE: Ogut T, Akgun I, Kesmezacar H, et al: Navigation for ankle arthroscopy: Anatomical study of the anterolateral portal with reference to the superficial peroneal nerve.  Surg Radiol Anat 2004;26:268-274.

Question 54

Which of the following body positions is associated with the highest intradiskal pressure?





Explanation

DISCUSSION: Intradiskal pressure is lowest when the patient is in the supine position.  Sitting is associated with higher intradiskal pressures than standing.  Flexion also increases intradiskal pressure.  The combination of flexion and sitting produces the highest intradiskal pressure.  Nachemson and Morris found that intradiskal pressure increases as position changes from lying supine, lying prone, standing, leaning forward, sitting, and sitting leaning forward.  Twisting or straining in positions of relatively high intradiskal pressure may predispose patients to herniation of the intervertebral disk.  Patients with a herniated disk may also notice their pain worsens with activities that increase the disk pressure, including the positions mentioned, or activities that increase intra-abdominal pressure (coughing, sneezing, straining).
REFERENCES: Nachemson A, Morris JM: In vivo measurements of intradiscal pressure. 

J Bone Joint Surg Am 1964;46:1077-1092.

Buckwalter JA, Einhorn TA, Simon SR (eds): Orthopaedic Basic Science: Biology and Biomechanics of the Musculoskeletal System, ed 2.  Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 547-556.

Question 55

A 56-year-old man underwent right total shoulder arthroplasty 2 months ago. Recently while reaching with his shoulder in a flexed and adducted position, he noted shoulder pain and afterwards he could not externally rotate his arm. An axillary radiograph is shown in Figure 30. What is the most likely cause of this problem?





Explanation

DISCUSSION: Anteversion of the humeral component may result in anterior instability of the component.  Posterior instability after total shoulder arthroplasty is usually the result of some combination of the following factors: untreated anterior soft-tissue contractures, excessive posterior capsular laxity, and excessive retroversion of the humeral and/or glenoid components.
REFERENCES: Cofield RH, Edgerton BC: Total shoulder arthroplasty: Complications and revision surgery.  Instr Course Lect 1990;39:449-462.
Wirth MA, Rockwood CA Jr: Complications of total shoulder replacement arthroplasty.  J Bone Joint Surg Am 1996;78:603-616.

Question 56

Figure 52 shows the MRI scan of a 28-year-old baseball pitcher. Examination will most likely reveal which of the following findings?





Explanation

DISCUSSION: A ganglion cyst compressing the suprascapular nerve results in poorly localized pain in the shoulder girdle.  Sensation is intact, with weakness of external rotation and abduction.  Supraspinatus and infraspinatus atrophy is often noted when viewed from behind.  These cysts are typically associated with labral tears.  Deltoid weakness is associated with an axillary nerve injury, and scapular winging results from injury to the long thoracic nerve. 
REFERENCES: Piatt BE, Hawkins RJ, Fritz RC, et al: Clinical evaluation and treatment of spinoglenoid notch ganglion cysts.  J Shoulder Elbow Surg 2002;11:600-604.
Inokuchi W, Ogawa K, Horiuchi V: Magnetic resonance imaging of suprascapular nerve palsy. 

J Shoulder Elbow Surg 1998;7:223-227.

Question 57

A 22-year-old man reports anterior knee pain, swelling, and is unable to perform a straight leg raise after undergoing endoscopic anterior cruciate ligament (ACL) reconstruction with a bone-patellar tendon-bone autograft 1 week ago. He is afebrile. Examination reveals a clean incision, moderate effusion, a weak isometric quadriceps contraction, active knee range of motion of 5 degrees to 45 degrees, and the patella is ballottable. Knee radiographs show postoperative changes with good femoral and tibial tunnel placements, and normal patellar height. What is the next most appropriate step in management?





Explanation

DISCUSSION: Knee pain and swelling in the first week after ACL reconstruction is usually related to a postoperative hemarthrosis.  A large hemarthrosis creates capsular distension, which inhibits active quadriceps contraction by a neurologic reflex, the H. reflex.  Kennedy and associates reported that an experimentally induced knee effusion at 60 mL was found to result in profound inhibition of reflexly evoked quadriceps contraction.  Removal of the hemarthrosis by aspiration will improve strength and often instantaneously restore the ability to contract the quadriceps muscle.  A large effusion will also limit knee flexion.  EMG and NCVS are not necessary unless there is a high index of suspicion of a femoral neuropathy.  Diagnostic ultrasonography is not necessary in this patient but can be useful in the assessment of patellar tendon integrity.  MRI is not indicated and would most likely be limited by artifact and postoperative changes.  Continuous passive motion is not indicated and would most likely worsen the patient’s symptoms.
REFERENCES: Kennedy JC, Alexander IJ, Hayes KC: Nerve supply of the human knee and its functional importance.  Am J Sports Med 1982;10:329-335.
Fahrer H, Rentsch HU, Gerber NJ, et al:  Knee effusion and reflex inhibition of the quadriceps: A bar to effective retraining.  J Bone Joint Surg Br 1988;70:635-638.

Question 58

A 19-year-old wrestler has numbness along the radial aspect of the forearm after undergoing an open Bankart repair through an anterior deltopectoral approach. Motor weakness would be expected along with what other finding?





Explanation

DISCUSSION: The musculocutaneous nerve may be injured by retracting the conjoined tendon medially.  This nerve enters the coracobrachialis 5 cm distal to its origin.  Its sensory distribution is the radial forearm, and its motor supply is to the biceps and brachialis.
REFERENCES: Bach BR, O’Brien SJ, Warren RF, et al: An unusual neurologic complication of the Bristow procedure.  J Bone Joint Surg Am 1988;70:458-460.
McIlveen SJ, Duralde XA: Isolated nerve injuries about the shoulder, in Bigliani LU (ed): Complications of Shoulder Surgery.  Baltimore, MD, Williams and Wilkins, 1993, pp 214-239.

Question 59

A 42-year-old woman underwent an instrumented posterior spinal fusion at L3-S1 with transforaminal lumbar interbody fusion. She had an excellent clinical result with complete resolution of leg pain. Three months later she now reports increasing back pain and weakness in her legs. Examination reveals weakness in the quadriceps and tibialis anterior. Radiographs show no interval changes in the position of the hardware. MRI scans are shown in Figures 2a through 2c. What is the next most appropriate step in management?





Explanation

DISCUSSION: The MRI scans reveal a postoperative infection.  Observation and antibiotics are not appropriate choices.  There is a large fluid collection and this requires decompression because the patient has neurologic changes.  There is considerable debate regarding the removal of hardware.  Many contend that biofilm on the implants can harbor the infection.  However, these complications usually can be treated with serial irrigations, debridements, and IV antibiotics.  The incidence of infection has been widely studied with varying rates in fusions with instrumentation.  Rates appear to be increased with instrumentation, yet these infections usually can be managed without hardware removal.
REFERENCES: Glassman SD, Dimar JR, Puno RM, et al: Salvage of instrumental lumbar fusions complicated by surgical wound infection.  Spine 1996;21:2163-2169.
Fang A, Hu SS, Endres N, et al: Risk factors for infection after spinal surgery.  Spine 2005;30:1460-1465.

Question 60

Of all the pelvic ring injury types, anteroposterior compression type III pelvic ring injuries have the highest rate of which of the following?





Explanation

DISCUSSION: Of the pelvic ring injuries, APC type III have the highest rate of mortality, blood loss, and need for transfusion. They also have a high rate of urogenital injury and abdominal organ injury. Lateral compression injuries (especially type III) have the highest rate of head injury. Vertical shear and combined injuries also have significant rates of concomitant injuries. The referenced article by Dalal et al is a review of Shock Trauma's pelvic ring injuries; they found significant increases in associated injuries as the grade of pelvic ring injury increased, regardless of mechanism/pattern. The aforementioned information was also found to be true with their patient review.

Question 61

What is the current 5-year survival rate for patients with classic nonmetastatic, high-grade osteosarcoma of the extremity?





Explanation

DISCUSSION: Multidisciplinary treatment combining systemic chemotherapy and adequate surgical resection has resulted in a 5-year survival rate of 70% in patients with nonmetastatic osteosarcoma of the extremity .  The advent of effective chemotherapy has increased the overall survival rate from 20% to 70% in current studies. 
REFERENCES: Arndt CA, Crist WM: Common musculoskeletal tumors of childhood and adolescence.  N Engl J Med 1999;341:342-352.
Glasser DB, Lane JM, Huvos AG, Marcove RC, Rosen G: Survival, prognosis, and therapeutic response in osteogenic sarcoma: The Memorial Hospital experience.  Cancer 1992;69:698-708.

Question 62

An  otherwise  healthy  76-year-old  woman  has  pain  2  years  after  total  hip  arthroplasty.  The  clinical photograph in Figures below demonstrates her skin envelope, and associated radiograph. Her C-reactive protein level is normal, and her erythrocyte sedimentation rate is mildly elevated. The white blood cell count is normal. Hip aspiration attempted under fluoroscopy generates no fluid. What is the best definitive treatment?




Explanation

DISCUSSION:
This patient clearly has a chronically infected total hip arthroplasty, indicated by the open, draining sinus, as well as trochanteric bone resorption on radiographs, and two years of pain. Recently, specific guidelines have  been  published  to  better  help  the  clinician  define  infection.  Repeating  the  hip  aspiration  is unnecessary, because infection is already evident. Initiating a wound care consult would not address the underlying  infection.  The  determination  whether  to  retain  the  components  or  perform  a  two-stage exchange  is  based  more  on  the  acuity  of  infection.  In  this  particular  case,  the  patient  is  chronically infected. Irrigation and debridement with a liner exchange and retention of the components are reserved for the acute setting.

Question 63

What structure is located at the tip of the arrow in Figure 18?





Explanation

DISCUSSION: The structure shown is the exiting nerve root at the L3-4 disk, which is the right L3 root.
REFERENCE: An H: Diagnostic imaging of the spine, in Principles and Techniques of Spine Surgery.  Baltimore, MD, Lippincott Williams & Wilkins, 1998, pp 102-125.

Question 64

Varus deformity after talar fractures is often seen due to collapse of the medial cortex. What artery supplies this portion of the talus?





Explanation

DISCUSSION: The artery of the tarsal canal is a branch of the posterior tibial artery.  Among the branches of the artery of the tarsal canal is the deltoid artery.  This arterial complex supplies the medial one third of the talar body.  Disruption of this artery may lead to osteonecrosis of the medial body and subsequent collapse into varus.  This is most commonly seen with talar body fractures but may be seen in Hawkins type 3 talar neck fractures.  The artery of the tarsal sinus arises from the dorsalis pedis, lateral malleolar, and perforating peroneal arteries.  The peroneal artery anastomoses with the calcaneal branches of the posterior tibial artery to form a plexus of vessels that supplies the posterior tubercle of the talus.  Disruption of this artery would not result in collapse of the medial body, and thus would not lead to a varus deformity.
REFERENCES: Halibruton RA, Sullivan CR, Kelly PJ, et al: The extra-osseous and intra-osseous blood supply of the talus.  J Bone Joint Surg Am 1958;40:1115.
Mulfinger GL, Trueta J: The blood supply of the talus.  J Bone Joint Surg Br 1970;52:160-167.

Question 65

Which of the following aids in correction of patellar tracking after total knee arthroplasty (TKA)?





Explanation

DISCUSSION: Correct patellofemoral tracking has proven to be a crucial aspect in TKA because a large percent of problems after TKA are related to the patellofemoral articulation.  External rotation of the femoral and tibial components has been shown to aid in tracking.  Likewise, medialization of the patellar button aids in patellar tracking and prevention of lateral subluxations and dislocations.  Attention to the distal femoral cut is critical in maintaining the joint line and preventing patella baja or alta.  Tibial sizing, however, is not directly related to patellar tracking after TKA.
REFERENCES: Callaghan JJ, Rosenberg AG, Rubash HE, et al (eds): The Adult Knee.  Philadelphia, PA, Lippincott Williams & Wilkins, 2003, pp 1245-1258.
Merkow RL, Soudry M, Insall JN:  Patellar dislocation following total knee replacement.  J Bone Joint Surg Am 1985;67:1321-1327.

Question 66

Which gene mutation or polymorphism has been shown to most increase the risk for venous thromboembolic disease after elective total joint arthroplasty?




Explanation

DISCUSSION
Simultaneous bilateral TKA accounts for approximately 6% of the TKAs performed in the United States and is more frequently performed for women. The incidence of pulmonary embolism in this group was between 0.57 and 1.14, according to a 1999 to 2008 registry-based study in the United States. There was not a significant change in incidence during that period. Hypoxemia alone is not an indication for advanced testing for pulmonary embolism. Winters and associates demonstrated that to avoid unnecessary testing, the use of a hypoxia algorithm is a reasonable first step. The use of pharmacologic agents and/or mechanical compressive devices for the prevention of venous thromboembolism in patients undergoing elective hip or knee arthroplasty and who are not at elevated risk beyond that of the surgery itself for venous thromboembolism or bleeding was given a Moderate grade of recommendation in the 2011 AAOS Clinical Practice Guideline, Preventing Venous Thromboembolic Disease in Patients Undergoing Elective Hip and Knee Arthroplasty. Various genetic factors are associated with increased risk for venous thromboembolic disease after TKA. A recent meta-analysis evaluated the genetic and polymorphism profiles associated with venous thromboembolism after arthroplasty. The mutation MTHFR/C677T/TT carried the highest risk (OR 2.36; 95% CI, 1.03-5.42, P = 0.04) for the gene mutations and polymorphisms studied. With the increased use of TXA as a blood-conservation strategy for total joint arthroplasty, there is a theoretical concern about an increased risk for venous thromboembolic disease. A recent study by Duncan and associates included 13,262 elective total joint arthroplasty procedures and demonstrated that TXA does not increase the risk of venous thromboembolism.

Question 67

A 47-year-old woman has a right bunion that has been symptomatic despite modifications in shoe wear. She requests surgical correction. An AP radiograph is shown in Figure 37. Treatment should consist of





Explanation

DISCUSSION: Because the radiograph reveals an intermetatarsal angle of greater than 15 degrees and an incongruent metatarsophalangeal joint, the treatment of choice is a proximal first metatarsal osteotomy with distal soft-tissue realignment.  A distal chevron procedure would not correct this degree of deformity.  A Keller procedure is reserved for a less active elderly individual.  Arthrodesis is appropriate for a patient with advanced arthritis of the metatarsophalangeal joint.  The double osteotomy is reserved for the congruent metatarsophalangeal joint with hallux valgus.
REFERENCES: Coughlin MJ, Carlson RE: Treatment of hallux valgus with an increased distal metatarsal articular angle: Evaluation of double and triple first ray osteotomies.  Foot Ankle Int 1999;20:762-770.
Coughlin MJ: Hallux valgus.  Instr Course Lect 1997;46:357-391.

Question 68

A 21-year-old man sustains multiple gunshot wounds to his right upper extremity. He can not extend his digits or his thumb but can extend and radially deviate his wrist. An injury to the radial nerve or one of its branches has most likely occurred at which of the following locations?





Explanation

DISCUSSION: In this patient, the radial nerve is most likely injured at the level of the radial neck.  The radial nerve emerges from the posterior cord of the brachial plexus and travels along the spiral groove of the humerus.  At the level of the lateral humeral condyle, the radial nerve branches into the posterior interosseous nerve after giving off two cutaneous branches, the superficial radial and the posterior cutaneous.  The posterior interosseous nerve travels through the supinator muscle and winds around the radial neck.  At this level, the posterior interosseous nerve is vulnerable to injury, particularly following fracture or penetrating trauma. 
REFERENCES: Netter F: The Ciba Collection of Medical Illustrations: The Musculoskeletal System, Part 1: Anatomy, Physiology and Metabolic Disorders.  West Caldwell, NJ, Ciba-Geigy Corporation, 1987, vol 8, p 53.
Hollinshead W: Anatomy for Surgeons: The Back and Limbs, ed 3.  Philadelphia, PA, Harper and Row, 1982, vol 3, pp 428-429.

Question 69

A 42-year-old woman sustains a closed posterior elbow dislocation. A closed reduction is performed, and the elbow appears stable under fluoroscopic examination. Initial treatment should consist of




Explanation

This is a simple (no associated fracture) elbow dislocation. Such dislocations can be treated with closed reduction followed by mobilization after 5 to 7 days to avoid stiffness, provided the elbow is stable through a full arc of motion at the time of reduction. If the elbow is unstable but has a short arc of stability, then using a hinged brace in the stable arc may be considered. (Note: It may be necessary to splint the elbow in pronation if the medial collateral ligament [MCL] is intact and the lateral collateral ligament [LCL] is disrupted, or in supination if the LCL is intact but the MCL disrupted.) Surgical reconstruction of the LCL and MCL may be required only if the elbow does not have a stable arc at the time of reduction. If unstable after reconstruction,
 application of a hinged external fixator may be considered.

Question 70

Exostoses in which of the following anatomic locations is the most likely to undergo malignant transformation in a patient with multiple hereditary exostosis (MHE)?





Explanation

DISCUSSION: Although osteochondromas can occur in almost every bone in patients with MHE, proximally located lesions are more likely to undergo malignant transformation.  Annual radiographs of the shoulder girdles and pelvis are indicated in patients with MHE.  Any enlarging osteochondromas are a concern as possible malignancies.
REFERENCES: Peterson HA: Multiple hereditary osteochondromata.  Clin Orthop 1989;239:222.
McCornack EB: The surgical management of hereditary multiple exostosis.  Orthop Rev 1981;10:57.

Question 71

A 4-month-old infant is referred for evaluation of congenital scoliosis. The child has no congenital heart anomalies, and a renal ultrasound shows that he has one kidney. Examination reveals mild scoliosis and a large hairy patch on the child’s back. Neurologic evaluation is normal for his age. A clinical photograph and radiograph are shown in Figures 19a and 19b. Initial management should consist of Review Topic





Explanation

Congenital anomalies of the spine, including failure of formation and failure of segmentation, are associated with other anomalies in other organ systems that develop at the same time. These include anomalies in the genitourinary system, cardiac anomalies, Sprengel’s deformity, radial hypoplasia, and gastrointestinal anomalies including imperforate anus and trachealesophageal fistula. Spinal dysraphism is the most common associated abnormality. McMaster found an 18% incidence before the common use of MRI. Bradford and associates reported on 16 of 42 patients with congenital spinal anomalies and spinal dysraphism using MRI. Neural axis lesions may be associated with visible midline abnormalities such as a hairy patch or nevus. The child has already had a cardiac and renal work-up, and based on the findings of the hairy patch and congenital vertebral anomalies, MRI of the entire spine is prudent at this time. Spinal fusion is indicated for progressive congenital scoliosis or kyphosis. Physical therapy does not affect the natural history of congenital scoliosis.

Question 72

What gene is expressed the earliest during the differentiation of a chondrocyte during endochondral ossification?





Explanation

DISCUSSION: Transcription factors regulate the activation or repression of cartilage-specific genes. Sox-9, considered a major regulator of chondrogenesis, regulates several cartilage-specific genes during endochondral ossification, including collagen types II, IV, and XI and aggrecan.
REFERENCES: Li J, Sandell LJ: Transcriptional regulation of cartilage-specific genes, in Rosier RN, Evans C (eds): Molecular Biology in Orthoapedics,  Rosemont, IL, American Academy of Orthopaedic Surgeons, 2002, pp 21-24.
Sandell LJ: Genes and gene expression.  Clin Orthop 2000;379:S9-S16.

Question 73

below shows the standing AP radiograph obtained from a year-old man who has a year history of daily left knee medial joint line pain with weight-bearing activities. He denies night pain or symptoms of instability. On examination, his range of motion is 0° to 140°. He has a mild, fully correctable varus deformity and a negative Lachman test result. Nonsurgical treatment has failed. Unicompartmental knee arthroplasty (UKA) is discussed with the patient. The most appropriate next radiographic evaluation should be



Explanation

DISCUSSION:
A  patient  with  medial  compartment  arthritis  and  a  correctable  varus  deformity  with  no  clinical  or examination findings of knee instability most likely has an intact anterior cruciate ligament (ACL). The pattern of medial compartment osteoarthritis most commonly associated with an intact ACL is that of anteromedial osteoarthritis. An incompetent ACL is commonly associated with a fixed varus deformity and radiographic signs of posteromedial wear. An incompetent ACL is a relative contraindication to a mobile-bearing UKA. When evaluating patients for a mobile-bearing UKA, a stress radiograph aids the orthopaedic  surgeon  in  determining  the  correction  of  the  varus  deformity  and  assessing  the  lateral compartment. An inability to fully correct the deformity or narrowing of the lateral compartment with valgus stress should influence the surgeon against UKA. Joint registries across the world have shown decreased  survivorship  associated  with  TKA  and  UKA  in  men  compared  with  other  age  groups,  but survivorship  is  lower  for  UKA  than  for  TKA.  No  studies  to  date  have  shown  any  differences  in survivorship  between  fixed-bearing  and  mobile-bearing  UKAs.  The  complication  that  is  unique  to mobile-bearing  UKA  is  bearing  spinout,  which  occurs  in  less  than  1%  of  mobile-bearing  UKA procedures. In vivo and in vitro polyethylene wear in mobile-bearing UKA are low. Arthritis may progress
faster in patients with mobile-bearing UKAs than in those with fixed-bearing UKAs.

Question 74

Survival rates for children with soft-tissue sarcoma other than rhabdomyosarcoma are best correlated with





Explanation

DISCUSSION: In review of 154 patients with nonrhabdomyosarcoma, Rao reported that histologic grade, tumor invasiveness, and adequate surgical margin were the most important prognostic factors.  Histologic subtype, use of adjuvant chemotherapy, and patient age were not as important.  Size related to degree of invasiveness was not statistically significant.
REFERENCES: Rao BN: Nonrhabdomyosarcoma in children: Prognostic factors influencing survival.  Semin Surg Oncol 1993;9:524-531.
Andrassy R, et al: Non-rhabdomyosarcoma Soft-Tissue Sarcomas: Pediatric Surgical Oncology.  Philadelphia, PA, WB Saunders, p 221.

Question 75

A 64-year-old man undergoes a primary total knee arthroplasty. Three months after surgery he reports persistent pain, weakness, and difficulty ambulating. Postoperative radiographs are shown in Figures 6a through 6c. What is the best course of action at this time?





Explanation

DISCUSSION: The Merchant view reveals subluxation of the patellar component.  The etiology of maltracking of the patella includes internal rotation of the femoral component, internal rotation of the tibial component, excessive patellar height, and lateralization of the patella component.  The treatment of choice in this patient is revision total knee arthroplasty with external rotation of the femoral component.  Preoperatively the patient also may require a lateral release, revision of the tibial component if it is internally rotated, and possibly a soft-tissue realignment.  Component malalignment needs to be addressed first. 
REFERENCES: Kelly MA: Extensor mechanism complications in total knee arthroplasty. 

Instr Course Lect 2004;53:193-199.

Malkani AL, Karandikar N: Complications following total knee arthroplasty.  Sem Arthroplasty 2003;14:203-214.
Norman AJ, Scott S, David GN (eds): Master Techniques in Knee Arthroplasty, ed 2.  Philadelphia, PA, Lippincott Williams & Wilkins, 2003.

Question 76

  • A 15-year-old girl has a thoracic kyphosis that causes mild pain. Examination reveals a sagittal curve measuring 55 degrees and wedging of the eighth through tenth vertebrae. The iliac apophyses are Risser 4. Management should include





Explanation

Scheuermann’s Disease classically presents with >45o thoracic kyphosis and anterior wedging (5o or more) at three sequential vertebrae. Disc narrowing, end-plate irregularities, scoliosis, spondylosis, and Schmorl’s nodes are also seen. It’s more common in adolescents and males. Normally, these patients are treated (1) in a brace if the curve is progressive and Risser 3 or less,
(2) with surgical fusion if >75o and Risser 3 or less, (3) with surgical fusion if >65o and Risser 4/5 if necessary or symptomatic. Posterior instrumentation, anterior release and interbody fusion is the treatment of choice for curves >75o, or those >55o on hyperextension. Other causes of kyphosis include trauma, infection, spondylitis, bone dysplasia, neoplasia, neurofibromatosis.

Question 77

A 43-year-old bus driver sustains a hyperextension injury to her arm and shoulder 4 months after undergoing an open Bankart repair. Examination reveals increased external rotation, anterior shoulder pain, and internal rotation weakness. Her examination also reveals the findings shown in Figure 44. What is the most likely diagnosis?





Explanation

DISCUSSION: An isolated tear of the subscapularis tendon has been noted as early as 1835 by Smith.  In Gerber and associates’ 1991 report of 16 men with an average age of 51 years, isolated subscapularis tendon rupture was often caused by a violent hyperextension injury.  All patients reported pain anteriorly along with night pain.  They also noted pain and weakness of the arm.  The lift-off test is performed by having the patient lift the palm of the hand away from the small of the back.  The patient must have sufficient internal rotation to allow this test to be performed.  A subscapularis rupture is likely if the patient cannot perform the lift-off test.
REFERENCES: Hertel R, Ballmer FT, Lombert SM, Gerber C: Lag signs in the diagnosis of rotator cuff rupture. J Shoulder Elbow Surg 1996;5:307-313. 
Gerber C, Krushell RJ: Isolated rupture of the tendon of the subscapularis muscle: Clinical features in 16 cases.  J Bone Joint Surg Br 1991;73:389-394. 
Greis PE, Kuhn JE, Schultheis J, Hintermeister R, Hawkins R: Validation of the lift-off test and analysis of subscapularis activity during maximal internal rotation. Am J Sports Med 1996;24:589-593. 
Gerber C, Hersche O, Farron A: Isolated rupture of the subscapularis tendon. J Bone Joint Surg Am 1996;78:1015-1023. 

Question 78

What is the principal advantage of surgical repair for the lesion shown in Figure 19?





Explanation

DISCUSSION: The MRI scan shows a rupture of the Achilles tendon.  The substantiated advantages of repair are less risk of re-rupture and greater plantar flexion strength.  Dorsiflexion strength is not influenced.  Motion, pain, and period of recovery are not specifically improved as a consequence of surgery.
REFERENCES: Bhandari M, Guyatt GH, Siddiqui F, et al: Treatment of acute Achilles tendon ruptures: A systematic overview and meta-analysis.  Clin Orthop 2002;400:190-200.
Schepsis AA, Jones HE, Haas AL: Achilles tendon disorders in athletes.  Am J Sports Med 2002;30:287-305.

Question 79

A 10-year-old girl who is Risser stage 0 has back deformity associated with neurofibromatosis type 1 (NF1). She has no back pain. Examination shows multiple cafe-au-lait nevi with normal lower extremity neurologic function and reflexes. Standing radiographs of the spine show a short 50-degree right thoracic scoliosis with a kyphotic deformity of 55 degrees (apex T8). A 10-degree progression in scoliosis has occurred during the past 1 year. There is no cervical deformity. MRI shows mild dural ectasia, primarily in the upper lumbar region. Management should consist of





Explanation

DISCUSSION: Scoliotic deformities in patients with NF1 are often dysplastic with short, angular curves.  Posterior arthrodesis is made more difficult by the presence of kyphosis and of weak posterior elements caused by dural ectasia.  Combined anterior and posterior spinal arthrodesis is generally preferred for progressive dysplastic curves to maximize deformity correction and to decrease the risk of pseudarthrosis.  Anterior fusion may also prevent crankshaft phenomenon in young children.  Brace treatment is not effective for large, rigid, or dysplastic curves.
REFERENCES: Kim HW, Weinstein SL: Spine update: The management of scoliosis in neurofibromatosis.  Spine 1997;22:2770-2776.
Funasaki H, Winter RB, Lonstein JB, et al: Pathophysiology of spinal deformities in neurofibromatosis: An analysis of seventy-one patients who had curves associated with dystrophic changes.  J Bone Joint Surg Am 1994;76:692-700.

Question 80

When harvesting an iliac crest bone graft from the posterior approach, what anatomic structure is at greatest risk for injury if a Cobb elevator is directed too caudal?





Explanation

DISCUSSION: If a Cobb elevator is directed caudally while stripping the periosteum over the iliac wing, it will encounter the sciatic notch.  Although this puts the sciatic nerve at risk, the first structure encountered is the superior gluteal artery.  Because it is tethered at the superior edge of the notch, it is very vulnerable to injury and can then retract inside the pelvis, making it difficult to obtain hemostasis.  The inferior gluteal artery exits the sciatic notch below the piriformis and is more protected.  The cluneal nerves are at risk only if the incision extends too anteriorly, and the sacroiliac joint can be entered while harvesting the graft.
REFERENCES: Banwart JC, Asher MA, Hassanein RS: Iliac crest bone graft harvest donor site morbidity: A statistical evaluation.  Spine 1995;20:1055-1060.
Shin AY, Moran ME, Wenger DR: Superior gluteal artery injury secondary to posterior iliac crest bone graft harvesting: A surgical technique to control hemorrhage.  Spine 1996;21:1371-1374.

Question 81

-Which type of cells has been implicated in the process shown inFigure?





Explanation

Question 82

Which of the following is considered a major characteristic of hyaluronate?





Explanation

DISCUSSION: Hyaluronate is a naturally occurring compound that is the backbone of the central core of the proteoglycan aggregate.  Cartilage is made of two principal tissue structures.  The connective tissue component includes collagen, which forms the framework for structural strength and elasticity.  The proteoglycan aggregate provides a unique property of water incorporation and friction reduction capabilities.  Hyaluronate forms the base or central core of the aggregate on which a link protein binds a protein core.  Chondroitin sulfate and keratin sulfate are then bound to this protein core, forming the terminal extension of the aggregate.
REFERENCES: Callaghan JJ, Dennis DA, Paprosky WA, Rosenberg AG (eds): Orthopedic Knowledge Update: Hip and Knee Reconstruction. Rosemont, IL, American Academy of Orthopaedic Surgeons, 1995, pp 69-78.
Felson DT: Osteoarthritis. Rheum Dis Clin North Am 1990;16:499-512.
Hurd ER: Extraarticular manifestations of rheumatoid arthritis. Semin Arthritis Rheum 1979;8:151-176.

Question 83

A 65-year-old woman undergoes a lumbar laminectomy for spinal stenosis at the L3-L4 level. The surgery and postsurgical course are uncomplicated. Eight weeks after surgery she has severe left anterior thigh, groin, and knee pain with ambulation and standing. Which condition is the most likely cause of her symptoms?




Explanation

DISCUSSION
Disorders of the hip can mimic and/or coexist with lumbar spine disorders. The prevalence of hip pain lasting longer than 1 month in patients ages 65 to 74 years is 19%. There is often overlap between their respective signs and symptoms. In a patient with failed back surgery syndrome, hip pathology may have been present before back surgery and not recognized. Osteoarthritis of
the hip typically causes groin and anterior thigh pain. Meralgia paraesthetica is more likely to manifest immediately after surgery. Trochanteric bursitis usually affects the proximal lateral thigh and often can radiate to the distal thigh. Facet joint pain causes low-back pain that can be referred to the gluteal region. Epidural hematoma 6 weeks after surgery is highly unlikely.
RECOMMENDED READINGS
Bolt PM, Wahl MM, Schofferman J: The roles of the hip, spine, sacroiliac joint, and other structures in patients with persistent pain after back surgery. Seminars in Spine surgery 2008;20:14-19.
Brown MD, Gomez-Marin O, Brookfield KF, Li PS. Differential diagnosis of hip disease versus spine disease. Clin Orthop Relat Res. 2004 Feb;(419):280-4. PubMed PMID: 15021166. View Abstract at PubMed

Question 84

An 18-year-old football player is injured after making a tackle with his left shoulder. He has decreased sensation over the lateral aspect of the left shoulder and radial aspect of the forearm. Motor examination reveals weakness to shoulder abduction and external rotation as well as elbow flexion. He has decreased reflexes of the biceps tendon on the left side but full, nontender range of motion of the cervical spine. What anatomic site has been injured? Review Topic





Explanation

The athlete has symptoms referable to the axillary, musculocutaneous, and suprascapular nerves resulting from an injury to the upper trunk of the brachial plexus. This portion of the plexus is formed by contributions of the fourth through sixth cervical nerve roots. This area is often contused or stretched following a tackling maneuver that results in either depression of the shoulder from contact at Erb’s point or traction of the upper plexus from forced stretching of the neck to the contralateral side.

Question 85

What is the most common bone tumor in the hand?





Explanation

DISCUSSION: The most common bone tumor in the hand is an enchondroma.  Forty-two percent of these lesions occur in the small tubular bones.  They frequently present with a fracture in these locations.  Fractures are usually treated nonsurgically.  Indications for surgery include patients with symptomatic lesions or those who are considered high risk for recurrent fracture. The histologic appearance of an enchondroma in the hand is more cellular than enchondromas found in the long bones.
REFERENCES: Menendez LR (ed): Orthopaedic Knowledge Update: Musculoskeletal Tumors.  Rosemont, IL, American Academy of Orthopaedic Surgeons, 2002, p 103.
Kuur E, Hansen SL, Lindequist S: Treatment of solitary enchondromas in fingers.  J Hand Surg Br 1989;14:109-112.

Question 86

Patient outcome after open reduction and internal fixation of tibial plateau fractures shows that patients older than 50 years of age when compared to younger patients have





Explanation

Several studies have shown worse functional results in patients older than 40 or 50 years of age compared to younger patients after open reduction and internal fixation of tibial plateau fractures. Two studies showed that older patients with less severe fractures performed less favorably than younger patients with more severe injuries. Only 35% of patients older than 50 years were satisfied with their results independent of fracture type.

Question 87

A senior resident is scheduled to perform a posterior medial release on a 10-month-old infant who has a congenital clubfoot deformity. Informed consent is obtained for the procedure. The supervising surgeon is obligated to give the parents what information?





Explanation

DISCUSSION: Informed consent is generally considered to be a process of mutual decision making between the physician and patient.  The physician is required to provide to the patient all material information that is needed for the patient to make an informed decision.  The courts have held that a patient’s choice of surgeon is as important to the consent as the procedure itself.  Assistance by a surgical trainee with adequate supervision is permissible when there has been adequate disclosure.  Adequate supervision may be defined as active participation by the attending during the essential parts of the procedure.  Allowing a substitute surgeon to operate on a patient without the patient’s knowledge “ghost surgery” may result in charges of battery against the substitute surgeon and malpractice against the surgeon to whom the patient

gave consent.

REFERENCES: Kocher MS: Ghost surgery: The ethical and legal implications of who does the operation.  J Bone Joint Surg Am 2002;84:148-150.
Holmes MK: Ghost surgery.  Bull NY Acad Med 1980;56:412-419.

Question 88

Figure 30 shows the radiograph of a 38-year-old man who reports persistent pain laterally and plantarly about the fifth metatarsal head. Examination reveals calluses dorsolaterally and plantarly about the fifth metatarsal head. Nonsurgical management has failed to provide relief. Surgical treatment should include





Explanation

DISCUSSION: The patient has painful lateral and plantar keratoses with metatarsus quintus valgus deformity.  This combination of problems is best addressed with an oblique mid-diaphyseal osteotomy that allows the distal metatarsal to be displaced medially and dorsally.  Lateral eminence resection alone will not address the painful plantar keratosis.  A distal chevron osteotomy has a more limited ability to address the plantar keratosis (if translated medially and slight dorsally).  Proximal diaphyseal osteotomies of the fifth metatarsal are associated with an increased risk of delayed union or nonunion secondary to the relative hypovascularity in the proximal diaphysis.  Excision of the fifth metatarsal head can result in a floppy fifth toe and transfer metatarsalgia. 
REFERENCES: Coughlin MJ: Treatment of bunionette deformity with longitudinal diaphyseal osteotomy with distal soft tissue repair.  Foot Ankle 1991;11:195-203.
Moran MM, Claridge RJ: Chevron osteotomy for bunionette.  Foot Ankle Int 1994;15:684-688.

Question 89

A 39-year-old man has had persistent right shoulder pain for the past 6 months. A formal physical therapy program has failed to provide relief, and an injection several months ago provided only short-term relief. Examination reveals a positive Neer and Hawkins test. There is no instability and the neurovascular examination is normal. Arthroscopy reveals a partial rotator cuff tear on the bursal side measuring 60% of the tendon thickness. What is the next most appropriate step in management?





Explanation

DISCUSSION: Although arthroscopic debridement with or without subacromial decompression is a reasonable response, the patient has positive impingement signs.  Several recent studies regarding the surgical treatment of partial rotator cuff tears have demonstrated good to excellent results after repair of tears involving more than 50% of the tendon thickness.  This was shown specifically for bursal-sided tears and joint-side tears.  Biceps tenotomy is not indicated in a young patient.
REFERENCES: Matava MJ, Purcell DB, Rudzki JR: Partial-thickness rotator cuff tears. 

Am J Sports Med 2005;33:1405-1417.

Fukuda H: The management of partial-thickness tears of the rotator cuff.  J Bone Joint Surg Br 2003;85:3-11.

Question 90

During what phase of the throwing motion is the highest torque measured across the glenohumeral joint?





Explanation

DISCUSSION: Electromyography is used to evaluate muscular firing patterns about the shoulder during the throwing sequence.  The rotator cuff muscles and biceps are relatively inactive during the acceleration phase, whereas the pectoralis major, serratus anterior, latissimus dorsi, and subscapularis show highest activity.  By contrast, deceleration is accomplished by the rotator cuff musculature and the larger trunk muscles acting in concert to slow down the arm.  It is during this phase of follow through that the highest torque is measured secondary to eccentric muscle contraction.
REFERENCES: Jobe FW, Moynes DR, Tibone JE, Perry J: An EMG analysis of the shoulder in pitching: A second report.  Am J Sports Med 1984;12:218-220.
Pappas AM, Zawacki RM, Sulliva TJ: Biomechanics of baseball pitching: A preliminary report.  Am J Sports Med 1985;13:216-222.
Altcheck DW, Dines DM: Shoulder injuries in the throwing athlete.  J Am Acad Orthop Surg 1995;3:159-165.

Question 91

A 25-year-old woman has significant pain and swelling in her left ankle after falling off her bicycle. Examination reveals that she is neurovascularly intact. Radiographs are shown in Figures 33a through 33c. What is the next most appropriate step in management?





Explanation

DISCUSSION: The radiographs show a displaced ankle fracture with widening of the syndesmosis.  Open reduction and internal fixation is indicated with fixation of the mortise with syndesmotic screws.
REFERENCES: Wuest TK: Injuries to the distal lower extremity syndesmosis.  J Am Acad Orthop Surg 1997;5:172-181.
Harper MC: Delayed reduction and stabilization of the tibiofibular syndesmosis.  Foot Ankle Int 2001;22:15-18.

Question 92

  • Successful healing of a meniscal repair is most likely associated é which of the following tear patterns?





Explanation

The blood supply to the meniscus has been well documented, and is primarily limited to the horns and outer one third of the meniscus. Both animal and human studies have clearly demonstrated healing of tears in the outer one third of the meniscus.
Arnoczky et al described the vascular supply to the meniscus and showed that tears within the outer one third of the meniscus have the best healing potential. Rim width is the most important prognostic factor for meniscal repairs; the vascular one third of the meniscus is most conductive to healing. Scott et al found better results when the tear was within 2mm of the meniscosynovial junction. Stone et al found improved healing with rim widths of 6mm or less. Tenuta et al found best results within a rim width of 3mm or less.

Question 93

Patients who have osteonecrosis of the humeral head and who have the best prognosis are those with which of the following conditions?





Explanation

DISCUSSION: The natural history of nontraumatic osteonecrosis varies greatly, so it is difficult to predict which patients will have severe arthrosis develop.  Patients with sickle cell disease tend to have the most benign course.  The most commonly reported cause of nontraumatic osteonecrosis is corticosteroid therapy.  Fortunately, the incidence of osteonecrosis among patients treated with long-term systemic corticosteroids has fallen from more than 25% to less than 5% in recent years, owning to judicious steroid use and dosing.  The interval between corticosteroid administration and the onset of shoulder symptoms is also variable, ranging from 6 to 18 months in one large series.  This is comparable to the interval leading up to the onset of hip symptoms, which ranges from 6 months to 3 years or longer.  The incidence of humeral head involvement has not been shown to vary with the underlying indication for steroid use.
REFERENCES: Hasan SS, Romeo AA: Nontraumatic osteonecrosis of the humeral head. 

J Shoulder Elbow Surg 2002;11:281-298.

Mansat P, Huser L, Mansat M, et al: Shoulder arthroplasty for atraumatic avascular necrosis of the humeral head: Nineteen shoulders followed up for a mean of seven years.  J Shoulder Elbow Surg 2005;14:114-120.

Question 94

Figure 21 shows the AP radiograph of a 41-year-old patient who sustained a closed bicolumnar fracture of the distal humerus that resulted in a painful nonunion. What is the best initial construct for rigid stabilization of this fracture pattern?





Explanation

DISCUSSION: The dual plate fixation construct is significantly stronger than single plate or “Y” plate fixation.  Two-plate constructs at right angles, the ulnar plate medially and the lateral plate posteriorly, would appear to be biomechanically optimal.  This approach usually is feasible at the time of surgery.  Clinically, dual 3.5-mm reconstruction or dynamic compression plates are superior to one third tubular plate fixation.  Supplementary external fixation is not considered a better treatment option.  Failure of fixation and nonunion are often the result of inadequate fixation and osteoporosis.
REFERENCES: Helfet DL, Hotchkiss RN: Internal fixation of the distal humerus: A biomechanical comparison of methods.  J Orthop Trauma 1990;4:260-264.
Sodergard J, Sandelin J, Bostman O: Mechanical failures of internal fixation in T and Y fractures of the distal humerus.  J Trauma 1992;33:687-690.

Question 95

Figures 31a and 31b show the T1- and T2-weighted MRI scans of a patient’s knee joint. What is the most likely diagnosis?





Explanation

DISCUSSION: The scans show a lipohemarthrosis.  There is the characteristic layering of a superior zone containing fat (high signal intensity), a central zone containing serum (low signal intensity), and an inferior zone that contains red blood cells (low signal intensity).  The most common cause of a lipohemarthrosis is an intra-articular fracture with leakage of marrow fat into the joint.
REFERENCES: Resnick D, Kang HS: Synovial joints, in Resnick D, Kang HS (eds): Internal Derangements of Joints: Emphasis on MR Imaging.  Philadelphia, PA, WB Saunders, 1997, pp 49-53.
Kier R, McCarthy SM: Lipohemarthrosis of the knee: MR imaging.  J Comput Assist Tomogr 1990;14:395-396.

Question 96

A 54-year-old man with metastatic renal cell carcinoma has had increasing pain in the left hip for the past 6 weeks. A radiograph is shown in Figure 36. Prophylactic stabilization will most likely result in





Explanation

DISCUSSION: Prophylactic stabilization of impending fractures does not directly affect the overall survival rate, but it does improve factors related to intraoperative and postoperative complications and decreased recovery time.
REFERENCES: Mirels H: Metastatic disease in long bones: A proposed scoring system for diagnosing impending pathologic fractures.  Clin Orthop 1989;249:256-264.
Harrington KD: Impending pathologic fractures from metastatic malignancy: Evaluation and management.  Instr Course Lect 1986;35:357-381.

Question 97

During a posterior cruciate ligament-sacrificing total knee arthroplasty with anterior referencing, 8 mm of distal femur is resected. It is noted that the flexion gap is tight and the extension gap appears stable. What is the next most appropriate step in management?





Explanation

DISCUSSION: If the flexion gap is tight and the extension gap is correct, it is preferable to change only the flexion gap and leave the extension gap unchanged; therefore, the treatment of choice is to decrease the size of the femoral component.  The smaller component will be smaller in both medial-lateral as well as anterior-posterior dimensions.  A smaller anterior-posterior size will allow more space for the flexion gap without significantly affecting the extension gap.  Decreasing the size of the tibial polyethylene insert thickness or cutting more proximal tibia will affect both the flexion and extension gaps.  Cutting more distal femur will increase the extension gap and not change the flexion gap, making the described situation worse.  Cutting both the proximal tibia and distal femur will increase both the flexion and extension gaps.
REFERENCE: Pellicci PM, Tria AJ Jr, Garvin KL (eds): Orthopaedic Knowledge Update: Hip and Knee Reconstruction 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 281-286, 339-365.

Question 98

  • What is the treatment of choice for an adult who has an isolated fracture of the ulna at the junction of the distal and middle thirds, with 5 degrees apex dorsal angulation and 25% displacement?





Explanation

This is the correct answer for various reasons, based on the question. Key points isolated fracture, distal and middle thirds, and only 25% displace. The author is implying minimal displacement. According to Gebuhr, Holmich a fracture such as describe in the question which does not require close reduction and only initial mobilization are better satisfied with a functional brace. Their study revealed that elbow extension/flexion and forearm pronation/supination had no difference with long arm cast, but wrist extension/flexion greatly improved with the functional bracing. Selections (1) more indicated for midshaft (3) is not inappropriate, but the authors felt it was not necessary because there was greater patient satisfaction with functional bracing and same results except wrist motion was better. (4), (5) are indicated for greater severity of fracture and failed union.

Question 99

A 70-year-old man has a posterior dislocation 20 years after undergoing cementless THA with a metal-on-polyethylene bearing. Acetabular inclination is 55 degrees with neutral version. This is his third dislocation, and he has been treated with closed reduction 3 times during the past month. His ESR is 42 mm/h (reference range [rr], 0-20 mm/h) and CRP level is 16.2 mg/L (rr, 0.08-3.1 mg/L). Joint aspiration reveals a cell count of 865 cells (55% neutrophils).






Explanation

DISCUSSION
Treatment options for various pathologic conditions after THA can be challenging, and there are often multiple potential options. Question 91 involves a patient who has fractured a modular ceramic acetabular liner, and an isolated head and liner exchange should be sufficient. Question 92 involves a patient with markedly elevated serum metal ions and abductor dysfunction, suggesting poor bearing function and a probable adverse local tissue reaction (ALTR). Additionally, the acetabular component position is suboptimal, and complete
acetabular revision would be appropriate. Question 93 involves a patient with elevated serum metal ions, with cobalt disproportionately higher than chromium in a roughly 7:1 ratio, suggesting corrosive changes at the prosthetic femoral neck (trunnionosis). Cross-sectional imaging continues to be a key part of the evaluation and treatment of patients with metal reactions. This patient’s pain and Trendelenburg gait are suggestive of ALTR. An isolated head and liner exchange should be performed, typically using a ceramic head and titanium sleeve adapter. Question 94 involves late, recurrent instability, probably related to bearing surface wear and acetabular component position. Continued nonsurgical management is unlikely to succeed at this point, so it would be appropriate to proceed with acetabular component revision.

Question 100

A 42-year-old woman with a long-standing history of rheumatoid arthritis undergoes total shoulder arthroplasty for persistent pain that has failed to respond to nonsurgical management. Intraoperative radiographs reveal an oblique, minimally displaced fracture of the greater tuberosity. Based on these findings, what is the best course of action?





Explanation

DISCUSSION: The risk of intraoperative fracture in osteoporotic bone in patients with rheumatoid arthritis is significant.  Fractures most often occur during humeral head dislocation and positioning for canal reaming.  If the fracture occurs at the greater tuberosity, cerclage suture fixation of the tuberosity fracture with autogenous cancellous bone graft from the resected humeral head is the treatment of choice.
REFERENCES: Wright TW, Cofield RH: Humeral fractures after shoulder arthroplasty.  J Bone Joint Surg Am 1995;77:1340-1346.
Norris TR (ed): Orthopaedic Knowledge Update: Shoulder and Elbow.  Rosemont, IL, American Academy of Orthopaedic Surgeons, 1997, pp 215-225.
Frankle MA, Ondrovic LE, Markee BA, et al: Stability of tuberosity reattachment in proximal humeral hemiarthroplasty.  J Shoulder Elbow Surg 2002;11:413-420.

Dr. Mohammed Hutaif
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Prof. Dr. Mohammed Hutaif
Consultant Orthopedic & Spine Surgeon
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